NGFR Increases the Chemosensitivity of Colorectal Cancer Cells by Enhancing the Apoptotic and Autophagic Effects of 5-fluorouracil via the Activation of S100A9

NGFR Increases the Chemosensitivity of Colorectal Cancer Cells by Enhancing the Apoptotic and Autophagic Effects of 5-fluorouracil via the Activation of S100A9

Colorectal cancer (CRC) is currently the third leading cause of cancer-related deaths worldwide, and 5-fluorouracil (5-FU)-based chemotherapies serve as important adjuvant therapies before and after surgery for CRC. However, the efficacy of CRC chemotherapy is limited by chemoresistance, and therefo...

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Bibliographic Details
Main Authors: Hao Chen, Jintuan Huang, Chunyu Chen, Yingming Jiang, Xingzhi Feng, Yi Liao, Zuli Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
NGFR
S100A9
apoptosis
autophagy
chemosensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.652081/full

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