Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN
Background: In healthy blood donors, 2%–5% have isolated anti-HBc. Prevalence of hepatitis B, C and co- infection (HBV +HCV) among injection drug user is high. Hepatitis C suppress of HB SAg and may be hepatitis B presented only with isolated anti HBC. This study determined of prevalence o...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Bushehr University of Medical Sciences
2011-09-01
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| Series: | Iranian South Medical Journal |
| Subjects: | |
| Online Access: | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-232&slc_lang=en&sid=1 |
| _version_ | 1818142619221360640 |
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| author | Masoomeh Soufian Fatemeh Sadat Mahdaviani Nabiollah Izadi Ali Mousavinejad Hossein Sarmadian Nader Zarrinfar Manizheh Kahbazi Ali Asghar Farazi |
| author_facet | Masoomeh Soufian Fatemeh Sadat Mahdaviani Nabiollah Izadi Ali Mousavinejad Hossein Sarmadian Nader Zarrinfar Manizheh Kahbazi Ali Asghar Farazi |
| author_sort | Masoomeh Soufian |
| collection | DOAJ |
| description | Background: In healthy blood donors, 2%–5% have isolated anti-HBc. Prevalence of hepatitis B, C and co- infection (HBV +HCV) among injection drug user is high. Hepatitis C suppress of HB SAg and may be hepatitis B presented only with isolated anti HBC. This study determined of prevalence of isolated anti HBC among injection drug users and compare with blood donors in Arak city. Methods: A total 684 subjects (531voluntary blood donors and 153 injection drug users) in Arak, Iran were included in this study. Hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), anti-HBc, and hepatitis C antibody (anti-HCV) were tested in all subjects. Results: A total of 531 voluntary blood donors living in the city of Arak, in the Central Province of Iran, with a mean age of 36 ± 10.18 years (range 16–60 years) were enrolled in the study. Ninety-three percent of patients were male and 7% were female. Of the 531 cases, 11 subjects (2.1%) had isolated anti-HBc. A total of 153 injection drug users of Arak, in the Central Province of Iran, with a mean age of 30.66 ± 5.92 years (range 20-50 years) were enrolled in the study. All of them were male. Of the 153 cases, 12 subjects (7.84%) had isolated anti-HBc. All of 12 cases were HCV positive. Conclusion: Prevalence of isolated anti-HBc among injection drug users was 3. 73 fold in comparison with blood donors. For diagnosis of hepatitis B in this group test for anti-HBc will be done. Evaluation of occult hepatitis B in subject with isolated anti-HBc by exact method such as real time PCR is necessary. |
| first_indexed | 2024-12-11T11:18:39Z |
| format | Article |
| id | doaj.art-645a540b8c8d4474b7fd9064a5a49c33 |
| institution | Directory Open Access Journal |
| issn | 1735-4374 1735-6954 |
| language | English |
| last_indexed | 2024-12-11T11:18:39Z |
| publishDate | 2011-09-01 |
| publisher | Bushehr University of Medical Sciences |
| record_format | Article |
| series | Iranian South Medical Journal |
| spelling | doaj.art-645a540b8c8d4474b7fd9064a5a49c332022-12-22T01:09:14ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542011-09-01143173178Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRANMasoomeh Soufian0Fatemeh Sadat Mahdaviani1Nabiollah Izadi2Ali Mousavinejad3Hossein Sarmadian4Nader Zarrinfar5Manizheh Kahbazi6Ali Asghar Farazi7 Background: In healthy blood donors, 2%–5% have isolated anti-HBc. Prevalence of hepatitis B, C and co- infection (HBV +HCV) among injection drug user is high. Hepatitis C suppress of HB SAg and may be hepatitis B presented only with isolated anti HBC. This study determined of prevalence of isolated anti HBC among injection drug users and compare with blood donors in Arak city. Methods: A total 684 subjects (531voluntary blood donors and 153 injection drug users) in Arak, Iran were included in this study. Hepatitis B surface antigen (HBsAg), hepatitis B surface antibody (anti-HBs), anti-HBc, and hepatitis C antibody (anti-HCV) were tested in all subjects. Results: A total of 531 voluntary blood donors living in the city of Arak, in the Central Province of Iran, with a mean age of 36 ± 10.18 years (range 16–60 years) were enrolled in the study. Ninety-three percent of patients were male and 7% were female. Of the 531 cases, 11 subjects (2.1%) had isolated anti-HBc. A total of 153 injection drug users of Arak, in the Central Province of Iran, with a mean age of 30.66 ± 5.92 years (range 20-50 years) were enrolled in the study. All of them were male. Of the 153 cases, 12 subjects (7.84%) had isolated anti-HBc. All of 12 cases were HCV positive. Conclusion: Prevalence of isolated anti-HBc among injection drug users was 3. 73 fold in comparison with blood donors. For diagnosis of hepatitis B in this group test for anti-HBc will be done. Evaluation of occult hepatitis B in subject with isolated anti-HBc by exact method such as real time PCR is necessary.http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-232&slc_lang=en&sid=1isolated anti-HBc injection drug users prevalence hepatitis |
| spellingShingle | Masoomeh Soufian Fatemeh Sadat Mahdaviani Nabiollah Izadi Ali Mousavinejad Hossein Sarmadian Nader Zarrinfar Manizheh Kahbazi Ali Asghar Farazi Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN Iranian South Medical Journal isolated anti-HBc injection drug users prevalence hepatitis |
| title | Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN |
| title_full | Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN |
| title_fullStr | Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN |
| title_full_unstemmed | Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN |
| title_short | Comparison the prevalence of isolated Hepatitis B core antibody among injection drug users with blood donors in central province in IRAN |
| title_sort | comparison the prevalence of isolated hepatitis b core antibody among injection drug users with blood donors in central province in iran |
| topic | isolated anti-HBc injection drug users prevalence hepatitis |
| url | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-232&slc_lang=en&sid=1 |
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