Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation

Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation

Abstract Background Breast cancer (BC) is the most frequently diagnosed cancer in women. Altering glucose metabolism and its effects on cancer progression and treatment resistance is an emerging interest in BC research. For instance, combining chemotherapy with glucose-lowering drugs (2-deoxyglucose...

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Bibliographic Details
Main Authors: Rita Aoun, Christopher El Hadi, Roula Tahtouh, Rita El Habre, George Hilal
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Cancer Cell International
Subjects:
Breast cancer
Triple-negative breast cancer
Hormone receptor-positive subtype
2-deoxyglucose
Metformin
Glucose starvation
Online Access:https://doi.org/10.1186/s12935-022-02542-w

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