Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep.
In our ongoing project, which focuses on the introgression of Booroola/FecB gene and the myostatin (MSTN) gene into purebred Moghani sheep, we assessed the performance of second-generation Moghani crossbreds such as second crossbreds (F2) and initial backcross generation (BC1). These crossbreds were...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301629&type=printable |
| _version_ | 1797214683055259648 |
|---|---|
| author | Reza Talebi Mohsen Mardi Mehrshad Zeinalabedini Mehrbano Kazemi Alamouti Stéphane Fabre Mohammad Reza Ghaffari |
| author_facet | Reza Talebi Mohsen Mardi Mehrshad Zeinalabedini Mehrbano Kazemi Alamouti Stéphane Fabre Mohammad Reza Ghaffari |
| author_sort | Reza Talebi |
| collection | DOAJ |
| description | In our ongoing project, which focuses on the introgression of Booroola/FecB gene and the myostatin (MSTN) gene into purebred Moghani sheep, we assessed the performance of second-generation Moghani crossbreds such as second crossbreds (F2) and initial backcross generation (BC1). These crossbreds were generated through different mating systems, including in-breeding, outcrossing, first paternal backcrossing (PBC1), and first maternal backcrossing (MBC1). Notably, F2 strains exhibited lean tail, woolly fleece and a higher percentage of white coat color compared to BC1. The impact of mating systems and birth types on pre-weaning survival rates was found to be statistically significant (P < 0.0001), with singleton offspring resulting from paternal backcross showing a particularly substantial effect. The F2 crossbred lambs carrying the Booroola gene did not show a statistically significant difference in survivability compared to those carrying the MSTN gene, implying the Booroola prolificacy gene had no significant impact on survival outcomes. However, the occurrence of multiple births had a significant negative impact on lamb survival (P < 0.0001). The PBC1 sheep strains, specifically Texel Tamlet ram strains carrying the MSTN mutation, exhibited superior growth rates compared to others (P < 0.05). Interestingly, the MSTN mutation in the homozygous variant genotype significantly impacts growth rate before weaning compared to other genotypes and pure Moghani sheep (P < 0.05). In conclusion, this study objectively underscores the pivotal role of genetic factors, specifically through strategic mating systems like paternal backcrossing, in enhancing desired traits and growth rates in Moghani sheep, thereby contributing valuable insights to the field of sheep breeding programs. |
| first_indexed | 2024-04-24T11:18:04Z |
| format | Article |
| id | doaj.art-646782c2876f4c4e9d2c539131ecc1d6 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-24T11:18:04Z |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-646782c2876f4c4e9d2c539131ecc1d62024-04-11T05:32:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01194e030162910.1371/journal.pone.0301629Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep.Reza TalebiMohsen MardiMehrshad ZeinalabediniMehrbano Kazemi AlamoutiStéphane FabreMohammad Reza GhaffariIn our ongoing project, which focuses on the introgression of Booroola/FecB gene and the myostatin (MSTN) gene into purebred Moghani sheep, we assessed the performance of second-generation Moghani crossbreds such as second crossbreds (F2) and initial backcross generation (BC1). These crossbreds were generated through different mating systems, including in-breeding, outcrossing, first paternal backcrossing (PBC1), and first maternal backcrossing (MBC1). Notably, F2 strains exhibited lean tail, woolly fleece and a higher percentage of white coat color compared to BC1. The impact of mating systems and birth types on pre-weaning survival rates was found to be statistically significant (P < 0.0001), with singleton offspring resulting from paternal backcross showing a particularly substantial effect. The F2 crossbred lambs carrying the Booroola gene did not show a statistically significant difference in survivability compared to those carrying the MSTN gene, implying the Booroola prolificacy gene had no significant impact on survival outcomes. However, the occurrence of multiple births had a significant negative impact on lamb survival (P < 0.0001). The PBC1 sheep strains, specifically Texel Tamlet ram strains carrying the MSTN mutation, exhibited superior growth rates compared to others (P < 0.05). Interestingly, the MSTN mutation in the homozygous variant genotype significantly impacts growth rate before weaning compared to other genotypes and pure Moghani sheep (P < 0.05). In conclusion, this study objectively underscores the pivotal role of genetic factors, specifically through strategic mating systems like paternal backcrossing, in enhancing desired traits and growth rates in Moghani sheep, thereby contributing valuable insights to the field of sheep breeding programs.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301629&type=printable |
| spellingShingle | Reza Talebi Mohsen Mardi Mehrshad Zeinalabedini Mehrbano Kazemi Alamouti Stéphane Fabre Mohammad Reza Ghaffari Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. PLoS ONE |
| title | Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. |
| title_full | Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. |
| title_fullStr | Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. |
| title_full_unstemmed | Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. |
| title_short | Assessing the performance of Moghani crossbred lambs derived from different mating systems with Texel and Booroola sheep. |
| title_sort | assessing the performance of moghani crossbred lambs derived from different mating systems with texel and booroola sheep |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0301629&type=printable |
| work_keys_str_mv | AT rezatalebi assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep AT mohsenmardi assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep AT mehrshadzeinalabedini assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep AT mehrbanokazemialamouti assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep AT stephanefabre assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep AT mohammadrezaghaffari assessingtheperformanceofmoghanicrossbredlambsderivedfromdifferentmatingsystemswithtexelandbooroolasheep |