EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS

In this article, we present results of local treatment of purulent wounds caused by various agents, in 232 patients, using local immunocorrection techniques combined with therapeutic application of nitrogen monoxide (NO). A series of immunological, cytological, microbiological researches have been c...

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Main Authors: M. A. Khalilov, I. A. Snimchsikova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/96
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author M. A. Khalilov
I. A. Snimchsikova
author_facet M. A. Khalilov
I. A. Snimchsikova
author_sort M. A. Khalilov
collection DOAJ
description In this article, we present results of local treatment of purulent wounds caused by various agents, in 232 patients, using local immunocorrection techniques combined with therapeutic application of nitrogen monoxide (NO). A series of immunological, cytological, microbiological researches have been carried out, showing a direct antibacterial effect of myelopid has been defined, and appropriate criteria have been developed for scoring intensity of inflammation affecting soft tissues. A justification for combined therapy with NО and myelopid has been obtained, and a method of local treatment of wound infections has been offered and patented. Basing on these experimental and clinical studies, as well as dynamic indices of wound process, we have shown a benefit from local immunocorrection by means of combined NО/myelopid treatment for complex therapy of purulent wounds.
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spelling doaj.art-6468c86956fe46078b5ff41c95ebdf0f2024-04-22T13:07:32ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0112322723410.15789/1563-0625-2010-3-227-23494EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDSM. A. Khalilov0I. A. Snimchsikova1ГОУ ВПО «Орловский государственный университет», Медицинский институт, г. ОрелГОУ ВПО «Орловский государственный университет», Медицинский институт, г. ОрелIn this article, we present results of local treatment of purulent wounds caused by various agents, in 232 patients, using local immunocorrection techniques combined with therapeutic application of nitrogen monoxide (NO). A series of immunological, cytological, microbiological researches have been carried out, showing a direct antibacterial effect of myelopid has been defined, and appropriate criteria have been developed for scoring intensity of inflammation affecting soft tissues. A justification for combined therapy with NО and myelopid has been obtained, and a method of local treatment of wound infections has been offered and patented. Basing on these experimental and clinical studies, as well as dynamic indices of wound process, we have shown a benefit from local immunocorrection by means of combined NО/myelopid treatment for complex therapy of purulent wounds.https://www.mimmun.ru/mimmun/article/view/96wound processchronic woundslocal immunocorrectionmyelopidnо therapy.
spellingShingle M. A. Khalilov
I. A. Snimchsikova
EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
Медицинская иммунология
wound process
chronic wounds
local immunocorrection
myelopid
nо therapy.
title EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
title_full EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
title_fullStr EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
title_full_unstemmed EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
title_short EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS
title_sort experience in local immunocorrection in treatment of chronic wounds
topic wound process
chronic wounds
local immunocorrection
myelopid
nо therapy.
url https://www.mimmun.ru/mimmun/article/view/96
work_keys_str_mv AT makhalilov experienceinlocalimmunocorrectionintreatmentofchronicwounds
AT iasnimchsikova experienceinlocalimmunocorrectionintreatmentofchronicwounds