Molecular mechanism of ATF6 in unfolded protein response and its role in disease

Molecular mechanism of ATF6 in unfolded protein response and its role in disease

Activating transcription factor 6 (ATF6), an important signaling molecule in unfolded protein response (UPR), plays a role in the pathogenesis of several diseases, including diseases such as congenital retinal disease, liver fibrosis and ankylosing spondylitis. After endoplasmic reticulum stress (ER...

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Bibliographic Details
Main Authors:	Yingying Lei, Hong Yu, Shaoxue Ding, Hui Liu, Chunyan Liu, Rong Fu
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Series:	Heliyon
Subjects:	Proteostasis Endoplasmic reticulum stress (ERS) Unfolded protein response (UPR) Activating transcription factor 6 (ATF6)
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024019686

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