3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome
Minimally invasive options are safe and reliable alternatives for the treatment of nutcracker syndrome (NCS). After continued efforts, our team successfully devised a new and effective therapeutic method: 3D-printed extravascular stenting of the left renal vein. From December 2017 to May 2019, 28 pa...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-07-01
|
| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00732/full |
| _version_ | 1818934362886897664 |
|---|---|
| author | Dali He Jiahe Liang Hengen Wang Yong Jiao Bin Wu Dong Cui Tiesheng Cao Yanyan Li Jing Wang Bo Zhang |
| author_facet | Dali He Jiahe Liang Hengen Wang Yong Jiao Bin Wu Dong Cui Tiesheng Cao Yanyan Li Jing Wang Bo Zhang |
| author_sort | Dali He |
| collection | DOAJ |
| description | Minimally invasive options are safe and reliable alternatives for the treatment of nutcracker syndrome (NCS). After continued efforts, our team successfully devised a new and effective therapeutic method: 3D-printed extravascular stenting of the left renal vein. From December 2017 to May 2019, 28 patients (25 men and 3 women) from different parts of China between 18 and 37 years old (mean, 23.6 years) diagnosed with NCS were admitted for laparoscopic 3D-printed extravascular stenting treatment. The post-operative follow-up duration was 6–24 months (median, 16.3 months). Technical success of the operation was achieved in all patients. After treatment, the NCS symptoms all patients resolved or improved during the follow-up period, without relapse. Most symptoms, including macro-/microhematuria, proteinuria, and flank/abdominal pain, tended to resolve within 3–6 months after the surgery; other symptoms, such as left-sided varicocele, also showed varying degrees of improvement at different times post-operatively. Perioperative complications were noted in two patients, including transient and mild lymphatic leakage, without any adverse effects. All extravascular stents were visualized on computed tomography and Doppler ultrasound scans, and no migration or any side effects occurred during the entire follow-up period. Compared to endovascular stenting or polytetrafluoroethylene artificial vessel procedures, 3D-printed polyetheretherketone extravascular stenting has more advantages in terms of stent design and rigidity and approach rationality while successfully preventing stent migration and thrombosis. Therefore, this method may serve as an accurate and effective treatment for NCS patients. |
| first_indexed | 2024-12-20T05:03:05Z |
| format | Article |
| id | doaj.art-6473c9e30dfc4f45a2f5d77fe90e1647 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-12-20T05:03:05Z |
| publishDate | 2020-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-6473c9e30dfc4f45a2f5d77fe90e16472022-12-21T19:52:30ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852020-07-01810.3389/fbioe.2020.007325386913D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical OutcomeDali He0Jiahe Liang1Hengen Wang2Yong Jiao3Bin Wu4Dong Cui5Tiesheng Cao6Yanyan Li7Jing Wang8Bo Zhang9Department of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Ultrasound Diagnostic, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Ultrasound Diagnostic, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaDepartment of Radiology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaSchool of Chemical Engineering and Technology, Xi’an Jiaotong University, Xi’an, ChinaDepartment of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi’an, ChinaMinimally invasive options are safe and reliable alternatives for the treatment of nutcracker syndrome (NCS). After continued efforts, our team successfully devised a new and effective therapeutic method: 3D-printed extravascular stenting of the left renal vein. From December 2017 to May 2019, 28 patients (25 men and 3 women) from different parts of China between 18 and 37 years old (mean, 23.6 years) diagnosed with NCS were admitted for laparoscopic 3D-printed extravascular stenting treatment. The post-operative follow-up duration was 6–24 months (median, 16.3 months). Technical success of the operation was achieved in all patients. After treatment, the NCS symptoms all patients resolved or improved during the follow-up period, without relapse. Most symptoms, including macro-/microhematuria, proteinuria, and flank/abdominal pain, tended to resolve within 3–6 months after the surgery; other symptoms, such as left-sided varicocele, also showed varying degrees of improvement at different times post-operatively. Perioperative complications were noted in two patients, including transient and mild lymphatic leakage, without any adverse effects. All extravascular stents were visualized on computed tomography and Doppler ultrasound scans, and no migration or any side effects occurred during the entire follow-up period. Compared to endovascular stenting or polytetrafluoroethylene artificial vessel procedures, 3D-printed polyetheretherketone extravascular stenting has more advantages in terms of stent design and rigidity and approach rationality while successfully preventing stent migration and thrombosis. Therefore, this method may serve as an accurate and effective treatment for NCS patients.https://www.frontiersin.org/article/10.3389/fbioe.2020.00732/fullnutcracker syndrome3D printingpolyetheretherketoneextravascular stentlaparoscopy |
| spellingShingle | Dali He Jiahe Liang Hengen Wang Yong Jiao Bin Wu Dong Cui Tiesheng Cao Yanyan Li Jing Wang Bo Zhang 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome Frontiers in Bioengineering and Biotechnology nutcracker syndrome 3D printing polyetheretherketone extravascular stent laparoscopy |
| title | 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome |
| title_full | 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome |
| title_fullStr | 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome |
| title_full_unstemmed | 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome |
| title_short | 3D-Printed PEEK Extravascular Stent in the Treatment of Nutcracker Syndrome: Imaging Evaluation and Short-Term Clinical Outcome |
| title_sort | 3d printed peek extravascular stent in the treatment of nutcracker syndrome imaging evaluation and short term clinical outcome |
| topic | nutcracker syndrome 3D printing polyetheretherketone extravascular stent laparoscopy |
| url | https://www.frontiersin.org/article/10.3389/fbioe.2020.00732/full |
| work_keys_str_mv | AT dalihe 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT jiaheliang 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT hengenwang 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT yongjiao 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT binwu 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT dongcui 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT tieshengcao 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT yanyanli 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT jingwang 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome AT bozhang 3dprintedpeekextravascularstentinthetreatmentofnutcrackersyndromeimagingevaluationandshorttermclinicaloutcome |