Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.

Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.

Smyd1/Bop is an evolutionary conserved histone methyltransferase previously shown by conventional knockout to be critical for embryonic heart development. To further explore the mechanism(s) in a cell autonomous context, we conditionally ablated Smyd1 in the first and second heart fields of mice usi...

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Bibliographic Details
Main Authors: Tara L Rasmussen, Yanlin Ma, Chong Yon Park, June Harriss, Stephanie A Pierce, Joseph D Dekker, Nicolas Valenzuela, Deepak Srivastava, Robert J Schwartz, M David Stewart, Haley O Tucker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372598?pdf=render

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