Characterization of tumoricidal activities mediated by a novel immune cell regimen composing interferon-producing killer dendritic cells and tumor-specific cytotoxic T lymphocytes

Abstract Background Although immune cell therapy has long been used for treating solid cancer, its efficacy remains limited. Interferon (IFN)-producing killer dendritic cells (IKDCs) exhibit cytotoxicity and present antigens to relevant cells; thus, they can selectively induce tumor-associated antig...

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Bibliographic Details
Main Authors: Chih-Hao Fang, Wen-Fang Cheng, Ya-Fang Cheng, Keng-Li Lan, Jan-Mou Lee
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-12101-3