Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review
Pregnancy-induced hypertension (PIH) is one of the main causes of maternal mortality. Many first- and second-line drugs are available to treat the condition. Labetalol lowers blood pressure by blocking both α and β adrenergic receptors. It preserves uteroplacental blood flow efficiently. A systemic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of the Practice of Cardiovascular Sciences |
| Subjects: | |
| Online Access: | http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=3;spage=144;epage=151;aulast=Bej |
| _version_ | 1828066005345107968 |
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| author | Punyatoya Bej Sambhunath Das |
| author_facet | Punyatoya Bej Sambhunath Das |
| author_sort | Punyatoya Bej |
| collection | DOAJ |
| description | Pregnancy-induced hypertension (PIH) is one of the main causes of maternal mortality. Many first- and second-line drugs are available to treat the condition. Labetalol lowers blood pressure by blocking both α and β adrenergic receptors. It preserves uteroplacental blood flow efficiently. A systemic review was carried out to find the efficacy and safety of labetalol in the treatment of PIH. Three thousand twenty-six studies were retrieved in 20 years. Finally, 28 studies were selected after applying the review criteria. Twenty-three studies detected that labetalol had superior or similar action compared to other drugs in controlling hypertension in patients with preeclampsia and eclampsia. The systematic review concluded that labetalol is a safe, effective, first-choice of drug with few side effects in treating PIH. |
| first_indexed | 2024-04-10T23:23:07Z |
| format | Article |
| id | doaj.art-647c59f8ae0f4b66a6499be4b03329da |
| institution | Directory Open Access Journal |
| issn | 2395-5414 2454-2830 |
| language | English |
| last_indexed | 2024-04-10T23:23:07Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Practice of Cardiovascular Sciences |
| spelling | doaj.art-647c59f8ae0f4b66a6499be4b03329da2023-01-12T13:23:33ZengWolters Kluwer Medknow PublicationsJournal of the Practice of Cardiovascular Sciences2395-54142454-28302022-01-018314415110.4103/jpcs.jpcs_69_22Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic reviewPunyatoya BejSambhunath DasPregnancy-induced hypertension (PIH) is one of the main causes of maternal mortality. Many first- and second-line drugs are available to treat the condition. Labetalol lowers blood pressure by blocking both α and β adrenergic receptors. It preserves uteroplacental blood flow efficiently. A systemic review was carried out to find the efficacy and safety of labetalol in the treatment of PIH. Three thousand twenty-six studies were retrieved in 20 years. Finally, 28 studies were selected after applying the review criteria. Twenty-three studies detected that labetalol had superior or similar action compared to other drugs in controlling hypertension in patients with preeclampsia and eclampsia. The systematic review concluded that labetalol is a safe, effective, first-choice of drug with few side effects in treating PIH.http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=3;spage=144;epage=151;aulast=Bejeclampsiafetal outcomelabetalolmaternal outcomenifedipinepreeclampsiapregnancy-induced hypertension |
| spellingShingle | Punyatoya Bej Sambhunath Das Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review Journal of the Practice of Cardiovascular Sciences eclampsia fetal outcome labetalol maternal outcome nifedipine preeclampsia pregnancy-induced hypertension |
| title | Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review |
| title_full | Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review |
| title_fullStr | Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review |
| title_full_unstemmed | Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review |
| title_short | Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review |
| title_sort | effect of labetalol for treating patients with pregnancy induced hypertension a systematic review |
| topic | eclampsia fetal outcome labetalol maternal outcome nifedipine preeclampsia pregnancy-induced hypertension |
| url | http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=3;spage=144;epage=151;aulast=Bej |
| work_keys_str_mv | AT punyatoyabej effectoflabetalolfortreatingpatientswithpregnancyinducedhypertensionasystematicreview AT sambhunathdas effectoflabetalolfortreatingpatientswithpregnancyinducedhypertensionasystematicreview |