3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma

3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the leading cancers that contribute to a large number of deaths throughout the globe. The signal transducer and activator of transcription 3 (STAT3) is a tumorigenic protein that is overactivated in several human malignancies including HCC. In the present rep...

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Bibliographic Details
Main Authors: Chakrabhavi Dhananjaya Mohan, Min Hee Yang, Shobith Rangappa, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Tahani Awad Alahmadi, Amudha Deivasigamani, Kam Man Hui, Gautam Sethi, Kanchugarakoppal S. Rangappa, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
formylchromone
STAT3 signaling
hepatocellular carcinoma
SHP-2
apoptosis
Online Access:https://www.mdpi.com/2079-7737/11/1/29

Internet

https://www.mdpi.com/2079-7737/11/1/29

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