Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making

Clinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequat...

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Main Authors: SHI Xiuqing, YAN Siyu, HUANG Qiao, LI Xuhui, WANG Yongbo, MA Wenhao, SHANG Hongcai, JIN Yinghui
Format: Article
Language:zho
Published: Editorial Office of Medical Journal of Peking Union Medical College Hospital 2023-07-01
Series:Xiehe Yixue Zazhi
Subjects:
Online Access:https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217
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author SHI Xiuqing
YAN Siyu
HUANG Qiao
LI Xuhui
WANG Yongbo
MA Wenhao
SHANG Hongcai
JIN Yinghui
author_facet SHI Xiuqing
YAN Siyu
HUANG Qiao
LI Xuhui
WANG Yongbo
MA Wenhao
SHANG Hongcai
JIN Yinghui
author_sort SHI Xiuqing
collection DOAJ
description Clinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequate basis for clinical decision-making, thus forming the gap between the guidelines and clinical decisions. Real-world research can enhance the external validity of the guidelines, provide a basis for clinical decision-making, and offer localized evidence for the guidelines, evidence of cost-effectiveness and other evidence for the guidelines. It can also monitor the implementation of the guidelines and help to make up for the lack of evidence in the formulation of traditional guidelines. Therefore, high-quality real-world studies and real-world evidence may be considered in the guideline development process to facilitate guideline optimization and serve as an aid to guideline quality improvement.
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spelling doaj.art-647e44ab676f4b0481b034ed53238cfa2023-08-02T05:55:40ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-07-0114485986710.12290/xhyxzz.2022-0217Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision MakingSHI Xiuqing0YAN Siyu1HUANG Qiao2LI Xuhui3WANG Yongbo4MA Wenhao5SHANG Hongcai6JIN Yinghui7Department of Oncology, Yuhuangding Hospital of Yantai, Yantai, Shandong 264000, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaZhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDongzhimen Hospital of Beijing University of Traditional Chinese Medicine, Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese Medicine, Beijing 100700, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaClinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequate basis for clinical decision-making, thus forming the gap between the guidelines and clinical decisions. Real-world research can enhance the external validity of the guidelines, provide a basis for clinical decision-making, and offer localized evidence for the guidelines, evidence of cost-effectiveness and other evidence for the guidelines. It can also monitor the implementation of the guidelines and help to make up for the lack of evidence in the formulation of traditional guidelines. Therefore, high-quality real-world studies and real-world evidence may be considered in the guideline development process to facilitate guideline optimization and serve as an aid to guideline quality improvement.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217real-world studyreal-world evidenceclinical practice guidelinesexternal validity
spellingShingle SHI Xiuqing
YAN Siyu
HUANG Qiao
LI Xuhui
WANG Yongbo
MA Wenhao
SHANG Hongcai
JIN Yinghui
Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
Xiehe Yixue Zazhi
real-world study
real-world evidence
clinical practice guidelines
external validity
title Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
title_full Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
title_fullStr Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
title_full_unstemmed Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
title_short Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
title_sort real world research bridging the gap between clinical practice guidelines and clinical decision making
topic real-world study
real-world evidence
clinical practice guidelines
external validity
url https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217
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AT lixuhui realworldresearchbridgingthegapbetweenclinicalpracticeguidelinesandclinicaldecisionmaking
AT wangyongbo realworldresearchbridgingthegapbetweenclinicalpracticeguidelinesandclinicaldecisionmaking
AT mawenhao realworldresearchbridgingthegapbetweenclinicalpracticeguidelinesandclinicaldecisionmaking
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