Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making
Clinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequat...
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Format: | Article |
Language: | zho |
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2023-07-01
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Series: | Xiehe Yixue Zazhi |
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Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217 |
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author | SHI Xiuqing YAN Siyu HUANG Qiao LI Xuhui WANG Yongbo MA Wenhao SHANG Hongcai JIN Yinghui |
author_facet | SHI Xiuqing YAN Siyu HUANG Qiao LI Xuhui WANG Yongbo MA Wenhao SHANG Hongcai JIN Yinghui |
author_sort | SHI Xiuqing |
collection | DOAJ |
description | Clinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequate basis for clinical decision-making, thus forming the gap between the guidelines and clinical decisions. Real-world research can enhance the external validity of the guidelines, provide a basis for clinical decision-making, and offer localized evidence for the guidelines, evidence of cost-effectiveness and other evidence for the guidelines. It can also monitor the implementation of the guidelines and help to make up for the lack of evidence in the formulation of traditional guidelines. Therefore, high-quality real-world studies and real-world evidence may be considered in the guideline development process to facilitate guideline optimization and serve as an aid to guideline quality improvement. |
first_indexed | 2024-03-12T19:11:05Z |
format | Article |
id | doaj.art-647e44ab676f4b0481b034ed53238cfa |
institution | Directory Open Access Journal |
issn | 1674-9081 |
language | zho |
last_indexed | 2024-03-12T19:11:05Z |
publishDate | 2023-07-01 |
publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
record_format | Article |
series | Xiehe Yixue Zazhi |
spelling | doaj.art-647e44ab676f4b0481b034ed53238cfa2023-08-02T05:55:40ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-07-0114485986710.12290/xhyxzz.2022-0217Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision MakingSHI Xiuqing0YAN Siyu1HUANG Qiao2LI Xuhui3WANG Yongbo4MA Wenhao5SHANG Hongcai6JIN Yinghui7Department of Oncology, Yuhuangding Hospital of Yantai, Yantai, Shandong 264000, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaZhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDongzhimen Hospital of Beijing University of Traditional Chinese Medicine, Ministry of Education and Beijing Key Laboratory of Internal Medicine of Traditional Chinese Medicine, Beijing 100700, ChinaCenter for Evidence-based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaClinical practice guidelines are an important basis for clinical decision-making, but there are still many factors that prevent physicians from following the guidelines. One of the problems, the limited external validity of the guidelines, ultimately prevents the guidelines from providing an adequate basis for clinical decision-making, thus forming the gap between the guidelines and clinical decisions. Real-world research can enhance the external validity of the guidelines, provide a basis for clinical decision-making, and offer localized evidence for the guidelines, evidence of cost-effectiveness and other evidence for the guidelines. It can also monitor the implementation of the guidelines and help to make up for the lack of evidence in the formulation of traditional guidelines. Therefore, high-quality real-world studies and real-world evidence may be considered in the guideline development process to facilitate guideline optimization and serve as an aid to guideline quality improvement.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217real-world studyreal-world evidenceclinical practice guidelinesexternal validity |
spellingShingle | SHI Xiuqing YAN Siyu HUANG Qiao LI Xuhui WANG Yongbo MA Wenhao SHANG Hongcai JIN Yinghui Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making Xiehe Yixue Zazhi real-world study real-world evidence clinical practice guidelines external validity |
title | Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making |
title_full | Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making |
title_fullStr | Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making |
title_full_unstemmed | Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making |
title_short | Real World Research: Bridging the Gap Between Clinical Practice Guidelines and Clinical Decision Making |
title_sort | real world research bridging the gap between clinical practice guidelines and clinical decision making |
topic | real-world study real-world evidence clinical practice guidelines external validity |
url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0217 |
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