Oesophagostomum dentatum extract modulates T cell-dependent immune responses to bystander antigens and prevents the development of allergy in mice.

One third of the human population is currently infected by one or more species of parasitic helminths. Certain helminths establish long-term chronic infections resulting in a modulation of the host's immune system with attenuated responsiveness to "bystander" antigens such as allergen...

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Bibliographic Details
Main Authors: Irma Schabussova, Onisa Ul-Haq, Elisabeth Hoflehner, Johnnie Akgün, Angelika Wagner, Gerhard Loupal, Anja Joachim, Bärbel Ruttkowski, Rick M Maizels, Ursula Wiedermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699627?pdf=render

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