BHMPS Inhibits Breast Cancer Migration and Invasion by Disrupting Rab27a-Mediated EGFR and Fibronectin Secretion

BHMPS Inhibits Breast Cancer Migration and Invasion by Disrupting Rab27a-Mediated EGFR and Fibronectin Secretion

Our previous work demonstrated that (<i>E</i>)-<i>N</i>-benzyl-6-(2-(3, 4-dihydroxybenzylidene) hydrazinyl)-<i>N</i>-methylpyridine-3-sulfonamide (BHMPS), a novel synthetic inhibitor of Rab27aSlp(s) interaction, suppresses tumor cell invasion and metastasis. Here,...

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Bibliographic Details
Main Authors: Jeong-In Park, Kyung-Hee Song, Seong-Mook Kang, Jeeyong Lee, Seong-Jun Cho, Hyun Kyung Choi, Jiyeon Ahn, Jong-Kuk Park, Jaesung Kim, Sang-Gu Hwang, Dae-Seog Lim, Joon Kim, Seung-Youn Jung, Jie-Young Song
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
Rab GTPase
invasion
migration
vesicle trafficking
breast cancer
Online Access:https://www.mdpi.com/2072-6694/14/2/373

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