DNA damage: from chronic Inflammation to age-related deterioration

DNA damage: from chronic Inflammation to age-related deterioration

To lessen the wear and tear of existence, cells have evolved mechanisms that continuously sense DNA lesions, repair DNA damage and restore the compromised genome back to its native form. Besides genome maintenance pathways, multi-cellular organisms may also employ adaptive and innate immune mechanis...

Full description

Bibliographic Details
Main Authors: Anna Ioannidou, Evi Goulielmaki, George A Garinis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Genetics
Subjects:
Aging
DNA Damage
DNA Repair
Inflammation
Cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00187/full

Similar Items

Similar Items