Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns
The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2019-10-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1332 |
| _version_ | 1797700217776111616 |
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| author | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina |
| author_facet | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina |
| author_sort | M. E. Lozovskaya |
| collection | DOAJ |
| description | The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug resistant patterns of the disease; 21 children were exposed to drug susceptible tuberculosis.Results. In St. Petersburg in 2015-2017, MDR TB cases prevailed among adult index cases to whom children were exposed. The course of tuberculosis was the most severe in children exposed to MDR TB. Such children were treated with regimen IV with high efficacy achieved, taking into account the severity of the disease, age, concurrent disorders, and tolerability of the drugs, as well as drug resistance of the index case. |
| first_indexed | 2024-03-12T04:18:59Z |
| format | Article |
| id | doaj.art-64853c4f51d2484a8d1f5af00d04b699 |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2024-03-12T04:18:59Z |
| publishDate | 2019-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-64853c4f51d2484a8d1f5af00d04b6992023-09-03T10:34:24ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062019-10-01979222710.21292/2075-1230-2019-97-9-22-271332Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patternsM. E. Lozovskaya0A. S. Kurova1E. B. Vasilieva2L. V. Klochkova3N. A. Nikiforenko4A. V. Mosina5ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФСПб ГБУЗ «Детская инфекционная больница № 3»The objective: to characterize tuberculosis in children exposed todrug-resistant tuberculosis in St. Petersburg.Subjects and methods. 51 children exposed to tuberculosis in their families were enrolled into the study; of them, 23 children were exposed to MDR TB; 7 children were exposed to other drug resistant patterns of the disease; 21 children were exposed to drug susceptible tuberculosis.Results. In St. Petersburg in 2015-2017, MDR TB cases prevailed among adult index cases to whom children were exposed. The course of tuberculosis was the most severe in children exposed to MDR TB. Such children were treated with regimen IV with high efficacy achieved, taking into account the severity of the disease, age, concurrent disorders, and tolerability of the drugs, as well as drug resistance of the index case.https://www.tibl-journal.com/jour/article/view/1332туберкулез у детейочаг туберкулезалекарственная устойчивость мбтхимиотерапия туберкулеза |
| spellingShingle | M. E. Lozovskaya A. S. Kurova E. B. Vasilieva L. V. Klochkova N. A. Nikiforenko A. V. Mosina Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns Туберкулез и болезни лёгких туберкулез у детей очаг туберкулеза лекарственная устойчивость мбт химиотерапия туберкулеза |
| title | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_full | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_fullStr | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_full_unstemmed | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_short | Specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| title_sort | specific features of the clinical course and chemotherapy of tuberculosis in children exposed to tuberculosis with different drug resistance patterns |
| topic | туберкулез у детей очаг туберкулеза лекарственная устойчивость мбт химиотерапия туберкулеза |
| url | https://www.tibl-journal.com/jour/article/view/1332 |
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