Baicalin, a Potent Inhibitor of NF-κB Signaling Pathway, Enhances Chemosensitivity of Breast Cancer Cells to Docetaxel and Inhibits Tumor Growth and Metastasis Both In Vitro and In Vivo

Baicalin, a Potent Inhibitor of NF-κB Signaling Pathway, Enhances Chemosensitivity of Breast Cancer Cells to Docetaxel and Inhibits Tumor Growth and Metastasis Both In Vitro and In Vivo

ObjectiveThe aim of this study is to investigate the anti-cancer activity and sensibilization of baicalin (BA) against breast cancer (BC) cells.MethodsThe anti-proliferation of BA in BC cell lines was evaluated by MTT and colony formation assays. Apoptotic induction of BA was measured by flow cytome...

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Bibliographic Details
Main Authors: Anqi Zeng, Xin Liang, Shaomi Zhu, Chi Liu, Xiaohong Luo, Qinxiu Zhang, Linjiang Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
baicalin
metastasis
chemosensitivity
NF-κB
breast cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00879/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00879/full

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