Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil
ABSTRACT Porcine respiratory disease complex is a major health concern for the porcine industry, causing significant economic loss. In this study, a total of 156 samples from pigs referred to a diagnostic laboratory in Brazil for 15 months were analyzed by histopathology, bacterial isolation, PCR, a...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Minas Gerais
2022-06-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300497&tlng=en |
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| author | A. Arenales C.H. Santana A.C.R. Rolim E.M.M.S. Pereira E.F. Nascimento T.A. Paixão R.L. Santos |
| author_facet | A. Arenales C.H. Santana A.C.R. Rolim E.M.M.S. Pereira E.F. Nascimento T.A. Paixão R.L. Santos |
| author_sort | A. Arenales |
| collection | DOAJ |
| description | ABSTRACT Porcine respiratory disease complex is a major health concern for the porcine industry, causing significant economic loss. In this study, a total of 156 samples from pigs referred to a diagnostic laboratory in Brazil for 15 months were analyzed by histopathology, bacterial isolation, PCR, and immunohistochemistry. Multiple infections were common, so 42.3% of the pigs had more than one pathogen detected in the lungs. Swine influenza virus was detected in 25.0% of the cases. Porcine circovirus type 2 was detected in 7.1% of the pigs, which was often associated with Pasteurella multocida. In addition, one case of porcine circovirus type 3 infection associated with granulomatous pneumonia was diagnosed. Bacteria were isolated in 125 cases, namely Pasteurella multocida (34.0%), Glaesserella (Haemophilus) parasuis (35.2%), Streptococcus suis (13.5%), and Actinobacillus pleuropneumoniae (7.7%). Mycoplasma hyopneumoniae was identified in 7.0% of the cases, and 18.6% of pigs carried Salmonella sp. The most common patterns of pulmonary inflammation were broncopneumonia, bronchointerstitial pneumonia, and pleuritis, in that order. This study demonstrated that histopathology is an efficient tool along with other laboratorial diagnostic tests for establishing an etiologic diagnosis in cases of porcine respiratory disease complex. |
| first_indexed | 2024-12-12T05:54:02Z |
| format | Article |
| id | doaj.art-64908c6b54f04b3a992be016ff3ed5af |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-12-12T05:54:02Z |
| publishDate | 2022-06-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-64908c6b54f04b3a992be016ff3ed5af2022-12-22T00:35:37ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622022-06-0174349750810.1590/1678-4162-12439Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in BrazilA. Arenaleshttps://orcid.org/0000-0003-2503-0823C.H. Santanahttps://orcid.org/0000-0003-2053-6278A.C.R. Rolimhttps://orcid.org/0000-0002-8127-7292E.M.M.S. PereiraE.F. NascimentoT.A. Paixãohttps://orcid.org/0000-0001-8284-9902R.L. Santoshttps://orcid.org/0000-0002-4830-0470ABSTRACT Porcine respiratory disease complex is a major health concern for the porcine industry, causing significant economic loss. In this study, a total of 156 samples from pigs referred to a diagnostic laboratory in Brazil for 15 months were analyzed by histopathology, bacterial isolation, PCR, and immunohistochemistry. Multiple infections were common, so 42.3% of the pigs had more than one pathogen detected in the lungs. Swine influenza virus was detected in 25.0% of the cases. Porcine circovirus type 2 was detected in 7.1% of the pigs, which was often associated with Pasteurella multocida. In addition, one case of porcine circovirus type 3 infection associated with granulomatous pneumonia was diagnosed. Bacteria were isolated in 125 cases, namely Pasteurella multocida (34.0%), Glaesserella (Haemophilus) parasuis (35.2%), Streptococcus suis (13.5%), and Actinobacillus pleuropneumoniae (7.7%). Mycoplasma hyopneumoniae was identified in 7.0% of the cases, and 18.6% of pigs carried Salmonella sp. The most common patterns of pulmonary inflammation were broncopneumonia, bronchointerstitial pneumonia, and pleuritis, in that order. This study demonstrated that histopathology is an efficient tool along with other laboratorial diagnostic tests for establishing an etiologic diagnosis in cases of porcine respiratory disease complex.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300497&tlng=enPasteurella multocidainfluenzaStreptococcus suisMycoplasma hyopneumoniaeActinobacillus pleuropneumoniaeGlaesserella (Haemophilus) parasuisPorcine circovirus type 3 |
| spellingShingle | A. Arenales C.H. Santana A.C.R. Rolim E.M.M.S. Pereira E.F. Nascimento T.A. Paixão R.L. Santos Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil Arquivo Brasileiro de Medicina Veterinária e Zootecnia Pasteurella multocida influenza Streptococcus suis Mycoplasma hyopneumoniae Actinobacillus pleuropneumoniae Glaesserella (Haemophilus) parasuis Porcine circovirus type 3 |
| title | Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil |
| title_full | Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil |
| title_fullStr | Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil |
| title_full_unstemmed | Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil |
| title_short | Histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in Brazil |
| title_sort | histopathologic patterns and etiologic diagnosis of porcine respiratory disease complex in brazil |
| topic | Pasteurella multocida influenza Streptococcus suis Mycoplasma hyopneumoniae Actinobacillus pleuropneumoniae Glaesserella (Haemophilus) parasuis Porcine circovirus type 3 |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352022000300497&tlng=en |
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