Keratinocytes determine Th1 immunity during early experimental leishmaniasis.

Keratinocytes determine Th1 immunity during early experimental leishmaniasis.

Experimental leishmaniasis is an excellent model system for analyzing Th1/Th2 differentiation. Resistance to Leishmania (L.) major depends on the development of a L. major specific Th1 response, while Th2 differentiation results in susceptibility. There is growing evidence that the microenvironment...

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Bibliographic Details
Main Authors: Jan M Ehrchen, Kirsten Roebrock, Dirk Foell, Nadine Nippe, Esther von Stebut, Johannes M Weiss, Niels-Arne Münck, Dorothee Viemann, Georg Varga, Carsten Müller-Tidow, Hans-Joachim Schuberth, Johannes Roth, Cord Sunderkötter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20442861/pdf/?tool=EBI

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