The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice

The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice

Abstract Diabetic retinopathy (DR) is considered a primarily microvascular complication of diabetes. Müller glia cells are at the centre of the retinal neurovascular unit and play a critical role in DR. We therefore investigated Müller cell-specific signalling pathways that are altered in DR to iden...

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Bibliographic Details
Main Authors: Anna M. Pfaller, Lew Kaplan, Madalena Carido, Felix Grassmann, Nundehui Díaz-Lezama, Farhad Ghaseminejad, Kirsten A. Wunderlich, Sarah Glänzer, Oliver Bludau, Thomas Pannicke, Bernhard H. F. Weber, Susanne F. Koch, Boyan Bonev, Stefanie M. Hauck, Antje Grosche
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Neuroinflammation
Subjects:
Diabetic retinopathy
Müller glia
mRNA expression profiling
Glucocorticoid receptor signalling
Proteomic analysis
Online Access:https://doi.org/10.1186/s12974-024-03021-x

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