Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis
Intercorrelative relationships between various clinical and laboratory parameters in dogs with acute gastroenteritis were studied. In dogs with acute alimentary gastroenteritis (n = 31), pain rating scale score significantly (p 0.05) correlated with pulse rate (r = 0.58), respiratory rate (r = 0.50...
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| Format: | Article |
| Language: | English |
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Peoples’ Friendship University of Russia (RUDN University)
2023-09-01
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| Series: | RUDN Journal of Agronomy and Animal Industries |
| Subjects: | |
| Online Access: | https://agrojournal.rudn.ru/agronomy/article/viewFile/19930/16375 |
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| author | Arfenya S. Karamyan Eliza A. Kuprina Vladimir I. Lutsay Vladimir I. Kuznetsov Valentina I. Semenova |
| author_facet | Arfenya S. Karamyan Eliza A. Kuprina Vladimir I. Lutsay Vladimir I. Kuznetsov Valentina I. Semenova |
| author_sort | Arfenya S. Karamyan |
| collection | DOAJ |
| description | Intercorrelative relationships between various clinical and laboratory parameters in dogs with acute gastroenteritis were studied. In dogs with acute alimentary gastroenteritis (n = 31), pain rating scale score significantly (p 0.05) correlated with pulse rate (r = 0.58), respiratory rate (r = 0.50), hematocrit (r = 0.47), ESR (r = 0.72), number of erythrocytes (r = 0.50) and leukocytes (r = 0.77), concentration of albumins (r = -0.52), globulins (r = 0.59), 1-globulins (r = 0.49), 2-globulins (r = 0.42), -globulins (r = -0.36), -globulins (r = 0.59), C-reactive protein (r = 0.82), serum activity of ALT (r = 0.70), AST (r = 0.39), -amylase (r = 0.38), alkaline phosphatase (r = 0.83) and serum concentration of creatinine (r = 0.42), tumor necrosis factor- (r = 0.82), interleukin-4 (r = 0.92), interleukin-6 (r = 0.92), interferon- (r = 0.91), interleukin-1 (r = 0.85), interleukin-8 (r = 0.91). The following changes were noted in the body of dogs with acute gastroenteritis: local and systemic immune-inflammatory response activated, pain, intoxication, dehydration syndrome, disorders of motor, secretory, absorption, excretory function of gastrointestinal tract formed, secondary hepatopathy and pancreatopathy developed. In dogs with acute gastroenteritis, there were also statistically significant (p 0.05) correlations between the number of erythrocytes and hematocrit (r = 0.65), MCHC (r = 0.32), ESR (r = 0.35), hemoglobin concentration (r = 0.73) and leukocyte count (r = 0.35); between MCV and hematocrit (r = 0.62), MCHC (r = -0.64); between MCV and MCHC (r = -0.64); MCH and MCHC (r = 0.40); ESR and leukocyte count (r = 0.53). Changes in intercorrelative relationships between clinical and laboratory parameters in dogs with acute gastroenteritis can be considered as predictors of severity of the pathological process. |
| first_indexed | 2024-03-11T21:05:40Z |
| format | Article |
| id | doaj.art-6493e4e8309140bdaab3387d3a0f95a3 |
| institution | Directory Open Access Journal |
| issn | 2312-797X 2312-7988 |
| language | English |
| last_indexed | 2024-03-11T21:05:40Z |
| publishDate | 2023-09-01 |
| publisher | Peoples’ Friendship University of Russia (RUDN University) |
| record_format | Article |
| series | RUDN Journal of Agronomy and Animal Industries |
| spelling | doaj.art-6493e4e8309140bdaab3387d3a0f95a32023-09-29T13:18:23ZengPeoples’ Friendship University of Russia (RUDN University)RUDN Journal of Agronomy and Animal Industries2312-797X2312-79882023-09-0118341842710.22363/2312-797X-2023-18-3-418-42717039Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritisArfenya S. Karamyan0https://orcid.org/0000-0003-2112-673XEliza A. Kuprina1https://orcid.org/0000-0003-2916-7050Vladimir I. Lutsay2https://orcid.org/0009-0003-4668-2545Vladimir I. Kuznetsov3https://orcid.org/0000-0002-4739-6976Valentina I. Semenova4https://orcid.org/0000-0002-3932-776XRUDN UniversityBiotech UniversityBiotech UniversityRUDN UniversityRUDN UniversityIntercorrelative relationships between various clinical and laboratory parameters in dogs with acute gastroenteritis were studied. In dogs with acute alimentary gastroenteritis (n = 31), pain rating scale score significantly (p 0.05) correlated with pulse rate (r = 0.58), respiratory rate (r = 0.50), hematocrit (r = 0.47), ESR (r = 0.72), number of erythrocytes (r = 0.50) and leukocytes (r = 0.77), concentration of albumins (r = -0.52), globulins (r = 0.59), 1-globulins (r = 0.49), 2-globulins (r = 0.42), -globulins (r = -0.36), -globulins (r = 0.59), C-reactive protein (r = 0.82), serum activity of ALT (r = 0.70), AST (r = 0.39), -amylase (r = 0.38), alkaline phosphatase (r = 0.83) and serum concentration of creatinine (r = 0.42), tumor necrosis factor- (r = 0.82), interleukin-4 (r = 0.92), interleukin-6 (r = 0.92), interferon- (r = 0.91), interleukin-1 (r = 0.85), interleukin-8 (r = 0.91). The following changes were noted in the body of dogs with acute gastroenteritis: local and systemic immune-inflammatory response activated, pain, intoxication, dehydration syndrome, disorders of motor, secretory, absorption, excretory function of gastrointestinal tract formed, secondary hepatopathy and pancreatopathy developed. In dogs with acute gastroenteritis, there were also statistically significant (p 0.05) correlations between the number of erythrocytes and hematocrit (r = 0.65), MCHC (r = 0.32), ESR (r = 0.35), hemoglobin concentration (r = 0.73) and leukocyte count (r = 0.35); between MCV and hematocrit (r = 0.62), MCHC (r = -0.64); between MCV and MCHC (r = -0.64); MCH and MCHC (r = 0.40); ESR and leukocyte count (r = 0.53). Changes in intercorrelative relationships between clinical and laboratory parameters in dogs with acute gastroenteritis can be considered as predictors of severity of the pathological process.https://agrojournal.rudn.ru/agronomy/article/viewFile/19930/16375acute gastroenteritispainpathogenesiscorrelationinflammationimmunologyhematology |
| spellingShingle | Arfenya S. Karamyan Eliza A. Kuprina Vladimir I. Lutsay Vladimir I. Kuznetsov Valentina I. Semenova Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis RUDN Journal of Agronomy and Animal Industries acute gastroenteritis pain pathogenesis correlation inflammation immunology hematology |
| title | Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| title_full | Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| title_fullStr | Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| title_full_unstemmed | Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| title_short | Pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| title_sort | pathogenetic factors associated with formation of acute abdominal pain syndrome in dogs with gastroenteritis |
| topic | acute gastroenteritis pain pathogenesis correlation inflammation immunology hematology |
| url | https://agrojournal.rudn.ru/agronomy/article/viewFile/19930/16375 |
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