QS8: Fat Grafting Depletes Profibrotic Prrx1-positive Fibroblasts In Irradiated Skin And Mitigates Radiation-induced Groin Contracture

QS8: Fat Grafting Depletes Profibrotic Prrx1-positive Fibroblasts In Irradiated Skin And Mitigates Radiation-induced Groin Contracture

Purpose: Contracture is a long-term complication of radiotherapy (RT) that results from pathologic fibrosis of soft tissue in the radiation field. Fat grafting can regenerate fibrotic soft tissue by decreasing collagen density and reorganizing collagen fiber networks. Fibroblasts are the predominant...

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Bibliographic Details
Main Authors:	Mimi Rosealie Borrelli, MBBS, MSc, BSc, Sandeep Adem, MS, Michelle Griffin, PhD, MD, MS, Nestor Diaz, NA, Michael T. Longaker, MA, MD, Derrick Wan, MD
Format:	Article
Language:	English
Published:	Wolters Kluwer 2021-07-01
Series:	Plastic and Reconstructive Surgery, Global Open
Online Access:	http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000770132.45355.9e

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