Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface
Graphene-based laminar membranes exhibit remarkable ion sieving properties, but their monovalent ion selectivity is still low and much less than the natural ion channels. Inspired by the elementary structure/function relationships of biological ion channels embedded in biomembranes, a new strategy i...
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MDPI AG
2023-07-01
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| Online Access: | https://www.mdpi.com/1996-1944/16/15/5393 |
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| author | Xiaoyuan Wang Hanhan Yang Zhenmei Yu Zengtao Zhang Yong Chen |
| author_facet | Xiaoyuan Wang Hanhan Yang Zhenmei Yu Zengtao Zhang Yong Chen |
| author_sort | Xiaoyuan Wang |
| collection | DOAJ |
| description | Graphene-based laminar membranes exhibit remarkable ion sieving properties, but their monovalent ion selectivity is still low and much less than the natural ion channels. Inspired by the elementary structure/function relationships of biological ion channels embedded in biomembranes, a new strategy is proposed herein to mimic biological K<sup>+</sup> channels by using the graphene laminar membrane (GLM) composed of two-dimensional (2D) angstrom(Å)-scale channels to support a simple model of semi-biomembrane, namely oil/water (O/W) interface. It is found that K<sup>+</sup> is strongly preferred over Na<sup>+</sup> and Li<sup>+</sup> for transferring across the GLM-supported water/1,2-dichloroethane (W/DCE) interface within the same potential window (-0.1-0.6 V), although the monovalent ion selectivity of GLM under the aqueous solution is still low (K<sup>+</sup>/Na<sup>+</sup>~1.11 and K<sup>+</sup>/Li<sup>+</sup>~1.35). Moreover, the voltammetric responses corresponding to the ion transfer of NH<sub>4</sub><sup>+</sup> observed at the GLM-supported W/DCE interface also show that NH<sub>4</sub><sup>+</sup> can often pass through the biological K<sup>+</sup> channels due to their comparable hydration–free energies and cation-π interactions. The underlying mechanism of as-observed K<sup>+</sup> selective voltammetric responses is discussed and found to be consistent with the energy balance of cationic partial-dehydration (energetic costs) and cation-π interaction (energetic gains) as involved in biological K<sup>+</sup> channels. |
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| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-11T00:23:23Z |
| publishDate | 2023-07-01 |
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| series | Materials |
| spelling | doaj.art-64945f837b50439c9b02bb6cb8be1cee2023-11-18T23:12:43ZengMDPI AGMaterials1996-19442023-07-011615539310.3390/ma16155393Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water InterfaceXiaoyuan Wang0Hanhan Yang1Zhenmei Yu2Zengtao Zhang3Yong Chen4School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, ChinaSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, ChinaSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, ChinaSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, ChinaSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, ChinaGraphene-based laminar membranes exhibit remarkable ion sieving properties, but their monovalent ion selectivity is still low and much less than the natural ion channels. Inspired by the elementary structure/function relationships of biological ion channels embedded in biomembranes, a new strategy is proposed herein to mimic biological K<sup>+</sup> channels by using the graphene laminar membrane (GLM) composed of two-dimensional (2D) angstrom(Å)-scale channels to support a simple model of semi-biomembrane, namely oil/water (O/W) interface. It is found that K<sup>+</sup> is strongly preferred over Na<sup>+</sup> and Li<sup>+</sup> for transferring across the GLM-supported water/1,2-dichloroethane (W/DCE) interface within the same potential window (-0.1-0.6 V), although the monovalent ion selectivity of GLM under the aqueous solution is still low (K<sup>+</sup>/Na<sup>+</sup>~1.11 and K<sup>+</sup>/Li<sup>+</sup>~1.35). Moreover, the voltammetric responses corresponding to the ion transfer of NH<sub>4</sub><sup>+</sup> observed at the GLM-supported W/DCE interface also show that NH<sub>4</sub><sup>+</sup> can often pass through the biological K<sup>+</sup> channels due to their comparable hydration–free energies and cation-π interactions. The underlying mechanism of as-observed K<sup>+</sup> selective voltammetric responses is discussed and found to be consistent with the energy balance of cationic partial-dehydration (energetic costs) and cation-π interaction (energetic gains) as involved in biological K<sup>+</sup> channels.https://www.mdpi.com/1996-1944/16/15/5393graphene laminar membraneoil/water interfaceangstrom-scaleion transfercation-π interaction |
| spellingShingle | Xiaoyuan Wang Hanhan Yang Zhenmei Yu Zengtao Zhang Yong Chen Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface Materials graphene laminar membrane oil/water interface angstrom-scale ion transfer cation-π interaction |
| title | Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface |
| title_full | Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface |
| title_fullStr | Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface |
| title_full_unstemmed | Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface |
| title_short | Two-Dimensional Graphene-Based Potassium Channels Built at an Oil/Water Interface |
| title_sort | two dimensional graphene based potassium channels built at an oil water interface |
| topic | graphene laminar membrane oil/water interface angstrom-scale ion transfer cation-π interaction |
| url | https://www.mdpi.com/1996-1944/16/15/5393 |
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