Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma

This study evaluated the effects of the immunobiological preparation "Interferon inducer bacterial liquid" (IIBI) combined with chemoradiotherapy (CRT) in patients with refractory Hodgkin’s lymphoma (HL) are presented. The clinical application of IIBI increases the efficacy of treatment. I...

Full description

Bibliographic Details
Main Authors: Daniar R. Aspetov, Maria N. Omarova, Lyazzat Zh. Orakbay, Raiymkul K. Karakulov, Kairat S. Doskhozhayev, Bayan Kh. Zhumatova, Meruyert D. Chazhayeva
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2015-12-01
Series:International Journal of Biomedicine
Subjects:
Online Access:http://ijbm.org/articles/Article5(4)_OA9.pdf
_version_ 1818609254496468992
author Daniar R. Aspetov
Maria N. Omarova
Lyazzat Zh. Orakbay
Raiymkul K. Karakulov
Kairat S. Doskhozhayev
Bayan Kh. Zhumatova
Meruyert D. Chazhayeva
author_facet Daniar R. Aspetov
Maria N. Omarova
Lyazzat Zh. Orakbay
Raiymkul K. Karakulov
Kairat S. Doskhozhayev
Bayan Kh. Zhumatova
Meruyert D. Chazhayeva
author_sort Daniar R. Aspetov
collection DOAJ
description This study evaluated the effects of the immunobiological preparation "Interferon inducer bacterial liquid" (IIBI) combined with chemoradiotherapy (CRT) in patients with refractory Hodgkin’s lymphoma (HL) are presented. The clinical application of IIBI increases the efficacy of treatment. IIBI in combination with CRT induces the production of highly active endogenous IFN-α/β, provides a marked regression of the affected lymph nodes in a short period (within 7 to 10 days) of treatment, relieves B symptoms, and increases by 2 times the length of remission in patients with refractory HL.
first_indexed 2024-12-16T14:55:37Z
format Article
id doaj.art-6495192baa734409ba7ff5d49832bcd6
institution Directory Open Access Journal
issn 2158-0510
2158-0529
language English
last_indexed 2024-12-16T14:55:37Z
publishDate 2015-12-01
publisher International Medical Research and Development Corporation
record_format Article
series International Journal of Biomedicine
spelling doaj.art-6495192baa734409ba7ff5d49832bcd62022-12-21T22:27:28ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292015-12-0154214218Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s LymphomaDaniar R. Aspetov0Maria N. Omarova1Lyazzat Zh. Orakbay2Raiymkul K. Karakulov3Kairat S. Doskhozhayev4Bayan Kh. Zhumatova5Meruyert D. Chazhayeva6Scientific Centre of Hygiene and Epidemiology; Almaty, KazakhstanScientific Centre of Hygiene and Epidemiology; Almaty, KazakhstanScientific Centre of Hygiene and Epidemiology; Almaty, KazakhstanKazakh Research Institute of Oncology and Radiology; Almaty, KazakhstanKazakh Research Institute of Oncology and Radiology; Almaty, KazakhstanScientific Centre of Hygiene and Epidemiology; Almaty, KazakhstanScientific Centre of Hygiene and Epidemiology; Almaty, KazakhstanThis study evaluated the effects of the immunobiological preparation "Interferon inducer bacterial liquid" (IIBI) combined with chemoradiotherapy (CRT) in patients with refractory Hodgkin’s lymphoma (HL) are presented. The clinical application of IIBI increases the efficacy of treatment. IIBI in combination with CRT induces the production of highly active endogenous IFN-α/β, provides a marked regression of the affected lymph nodes in a short period (within 7 to 10 days) of treatment, relieves B symptoms, and increases by 2 times the length of remission in patients with refractory HL.http://ijbm.org/articles/Article5(4)_OA9.pdfHodgkin’s lymphoma;chemoradiotherapy;immunotherapy;INF inducer;
spellingShingle Daniar R. Aspetov
Maria N. Omarova
Lyazzat Zh. Orakbay
Raiymkul K. Karakulov
Kairat S. Doskhozhayev
Bayan Kh. Zhumatova
Meruyert D. Chazhayeva
Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
International Journal of Biomedicine
Hodgkin’s lymphoma;
chemoradiotherapy;
immunotherapy;
INF inducer;
title Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
title_full Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
title_fullStr Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
title_full_unstemmed Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
title_short Clinical Use of the Interferon Inducer IIBI in Patients with Refractory Hodgkin’s Lymphoma
title_sort clinical use of the interferon inducer iibi in patients with refractory hodgkin s lymphoma
topic Hodgkin’s lymphoma;
chemoradiotherapy;
immunotherapy;
INF inducer;
url http://ijbm.org/articles/Article5(4)_OA9.pdf
work_keys_str_mv AT daniarraspetov clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT marianomarova clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT lyazzatzhorakbay clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT raiymkulkkarakulov clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT kairatsdoskhozhayev clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT bayankhzhumatova clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma
AT meruyertdchazhayeva clinicaluseoftheinterferoninduceriibiinpatientswithrefractoryhodgkinslymphoma