The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology
The genus <i>Lagochilus</i> (Lamiaceae) is native to Central, South-Central, and Eastern Asia. It comprises 44 species, which have been commonly used as herbal medicines for the treatments of various ailments for thousands of years, especially in Asian countries. This review aims to summ...
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MDPI AG
2021-01-01
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| Online Access: | https://www.mdpi.com/2223-7747/10/1/132 |
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| author | Nilufar Z. Mamadalieva Davlat Kh. Akramov Ludger A. Wessjohann Hidayat Hussain Chunlin Long Komiljon Sh. Tojibaev Elham Alshammari Mohamed L. Ashour Michael Wink |
| author_facet | Nilufar Z. Mamadalieva Davlat Kh. Akramov Ludger A. Wessjohann Hidayat Hussain Chunlin Long Komiljon Sh. Tojibaev Elham Alshammari Mohamed L. Ashour Michael Wink |
| author_sort | Nilufar Z. Mamadalieva |
| collection | DOAJ |
| description | The genus <i>Lagochilus</i> (Lamiaceae) is native to Central, South-Central, and Eastern Asia. It comprises 44 species, which have been commonly used as herbal medicines for the treatments of various ailments for thousands of years, especially in Asian countries. This review aims to summarize the chemical constituents and pharmacological activities of species from the genus <i>Lagochilus</i> to unveil opportunities for future research. In addition, we provide some information about their traditional uses, botany, and diversity. More than 150 secondary metabolites have been reported from <i>Lagochilus</i>, including diterpenes, flavonoids, phenolic compounds, triterpenoids, iridoid glycosides, lignans, steroids, alkaloids, polysaccharides, volatile, non-volatile and aromatic compounds, lipids, carbohydrates, minerals, vitamins, and other secondary metabolites. <i>In vitro</i> and <i>in vivo</i> pharmacological studies on the crude extracts, fractions, and isolated compounds from <i>Lagochilus</i> species showed hemostatic, antibacterial, anti-inflammatory, anti-allergic, cytotoxic, enzyme inhibitory, antispasmodic, hypotensive, sedative, psychoactive, and other activities. |
| first_indexed | 2024-03-09T05:15:56Z |
| format | Article |
| id | doaj.art-6499a21330d3405b94ca8bd68f0a3a56 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-09T05:15:56Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-6499a21330d3405b94ca8bd68f0a3a562023-12-03T12:45:56ZengMDPI AGPlants2223-77472021-01-0110113210.3390/plants10010132The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and PharmacologyNilufar Z. Mamadalieva0Davlat Kh. Akramov1Ludger A. Wessjohann2Hidayat Hussain3Chunlin Long4Komiljon Sh. Tojibaev5Elham Alshammari6Mohamed L. Ashour7Michael Wink8Institute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Mirzo Ulugbek Str 77, Tashkent 100170, UzbekistanInstitute of the Chemistry of Plant Substances of the Academy Sciences of Uzbekistan, Mirzo Ulugbek Str 77, Tashkent 100170, UzbekistanDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), GermanyDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), GermanyCollege of Life and Environmental Sciences, Minzu University of China, Beijing 100081, ChinaInstitute of Botany of the Academy Sciences of Uzbekistan, Durmon Yuli Str 32, Tashkent 100125, UzbekistanDepartment of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi ArabiaDepartment of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, Jeddah 21442, Saudi ArabiaDepartment of Pharmaceutical Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, 69120 Heidelberg, GermanyThe genus <i>Lagochilus</i> (Lamiaceae) is native to Central, South-Central, and Eastern Asia. It comprises 44 species, which have been commonly used as herbal medicines for the treatments of various ailments for thousands of years, especially in Asian countries. This review aims to summarize the chemical constituents and pharmacological activities of species from the genus <i>Lagochilus</i> to unveil opportunities for future research. In addition, we provide some information about their traditional uses, botany, and diversity. More than 150 secondary metabolites have been reported from <i>Lagochilus</i>, including diterpenes, flavonoids, phenolic compounds, triterpenoids, iridoid glycosides, lignans, steroids, alkaloids, polysaccharides, volatile, non-volatile and aromatic compounds, lipids, carbohydrates, minerals, vitamins, and other secondary metabolites. <i>In vitro</i> and <i>in vivo</i> pharmacological studies on the crude extracts, fractions, and isolated compounds from <i>Lagochilus</i> species showed hemostatic, antibacterial, anti-inflammatory, anti-allergic, cytotoxic, enzyme inhibitory, antispasmodic, hypotensive, sedative, psychoactive, and other activities.https://www.mdpi.com/2223-7747/10/1/132<i>Lagochilus</i>Lamiaceaediversitytraditional medicinephytochemistrysecondary metabolites |
| spellingShingle | Nilufar Z. Mamadalieva Davlat Kh. Akramov Ludger A. Wessjohann Hidayat Hussain Chunlin Long Komiljon Sh. Tojibaev Elham Alshammari Mohamed L. Ashour Michael Wink The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology Plants <i>Lagochilus</i> Lamiaceae diversity traditional medicine phytochemistry secondary metabolites |
| title | The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology |
| title_full | The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology |
| title_fullStr | The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology |
| title_full_unstemmed | The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology |
| title_short | The Genus <i>Lagochilus</i> (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology |
| title_sort | genus i lagochilus i lamiaceae a review of its diversity ethnobotany phytochemistry and pharmacology |
| topic | <i>Lagochilus</i> Lamiaceae diversity traditional medicine phytochemistry secondary metabolites |
| url | https://www.mdpi.com/2223-7747/10/1/132 |
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