Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country
Coxiella burnetii is the agent of Q fever, a disease that poses risks to public health and damages livestock. We discovered the circulation of C. burnetii for the first time in Paraguay, based on the seropositivity of a flock of >300 sheep. The animals were tested by IFA for anti-C. burnetii anti...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | One Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352771423001805 |
| _version_ | 1797388742019776512 |
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| author | Danilo Alves de França Filipe Pereira da Silva Dayane da Silva Zanini Lorena Iglesias Laura Portillo Herminia Cortez Alexander Welker Biondo Ana Íris de Lima Duré Marcos Vinicius Ferreira Silva Jorge Miret Helio Langoni |
| author_facet | Danilo Alves de França Filipe Pereira da Silva Dayane da Silva Zanini Lorena Iglesias Laura Portillo Herminia Cortez Alexander Welker Biondo Ana Íris de Lima Duré Marcos Vinicius Ferreira Silva Jorge Miret Helio Langoni |
| author_sort | Danilo Alves de França |
| collection | DOAJ |
| description | Coxiella burnetii is the agent of Q fever, a disease that poses risks to public health and damages livestock. We discovered the circulation of C. burnetii for the first time in Paraguay, based on the seropositivity of a flock of >300 sheep. The animals were tested by IFA for anti-C. burnetii antibodies and by SAM for anti-Leptospira spp. antibodies, an important differential diagnosis for reproductive disorders in sheep in Paraguay. C. burnetii seropositivity was determined in 45%, in contrast to Leptospira spp. which had no reactive samples. Cases of miscarriage and fetal resorption were associated with high seropositivity titers. This study suggests the circulation of a unique genotype in the country and an imminent risk to public health, since in addition to being highly transmissible and infectious to humans, Q fever is still not a cause for concern on the part of government and health agencies in the country. |
| first_indexed | 2024-03-08T22:45:13Z |
| format | Article |
| id | doaj.art-649aeb48257a45faa851d911ef484ff6 |
| institution | Directory Open Access Journal |
| issn | 2352-7714 |
| language | English |
| last_indexed | 2024-03-08T22:45:13Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | One Health |
| spelling | doaj.art-649aeb48257a45faa851d911ef484ff62023-12-17T06:40:07ZengElsevierOne Health2352-77142024-06-0118100660Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the countryDanilo Alves de França0Filipe Pereira da Silva1Dayane da Silva Zanini2Lorena Iglesias3Laura Portillo4Herminia Cortez5Alexander Welker Biondo6Ana Íris de Lima Duré7Marcos Vinicius Ferreira Silva8Jorge Miret9Helio Langoni10São Paulo State University, Prof. Doutor Walter Mauricio Correa, s/n, Unesp Campus de Botucatu, Botucatu, São Paulo 18618-681, BrazilOctavio Magalhaes Institute, Prof. Octavio Coelho De Magalhaes, s/n, Fundação Ezequiel Dias, Belo Horizonte 30210-290, Minas Gerais, BrazilSão Paulo State University, Prof. Doutor Walter Mauricio Correa, s/n, Unesp Campus de Botucatu, Botucatu, São Paulo 18618-681, BrazilUniversidad Nacional de Canindeyú, Calle Itambey, Curuguaty 140802, ParaguayUniversidad Nacional de Canindeyú, Calle Itambey, Curuguaty 140802, ParaguayUniversidad Nacional de Canindeyú, Calle Itambey, Curuguaty 140802, ParaguayFederal University of Paraná, Rua Dr Faivre, 405, Curitiba 140802, Paraná, BrazilOctavio Magalhaes Institute, Prof. Octavio Coelho De Magalhaes, s/n, Fundação Ezequiel Dias, Belo Horizonte 30210-290, Minas Gerais, BrazilOctavio Magalhaes Institute, Prof. Octavio Coelho De Magalhaes, s/n, Fundação Ezequiel Dias, Belo Horizonte 30210-290, Minas Gerais, BrazilUniversidad Nacional de Canindeyú, Calle Itambey, Curuguaty 140802, ParaguaySão Paulo State University, Prof. Doutor Walter Mauricio Correa, s/n, Unesp Campus de Botucatu, Botucatu, São Paulo 18618-681, Brazil; Corresponding author.Coxiella burnetii is the agent of Q fever, a disease that poses risks to public health and damages livestock. We discovered the circulation of C. burnetii for the first time in Paraguay, based on the seropositivity of a flock of >300 sheep. The animals were tested by IFA for anti-C. burnetii antibodies and by SAM for anti-Leptospira spp. antibodies, an important differential diagnosis for reproductive disorders in sheep in Paraguay. C. burnetii seropositivity was determined in 45%, in contrast to Leptospira spp. which had no reactive samples. Cases of miscarriage and fetal resorption were associated with high seropositivity titers. This study suggests the circulation of a unique genotype in the country and an imminent risk to public health, since in addition to being highly transmissible and infectious to humans, Q fever is still not a cause for concern on the part of government and health agencies in the country.http://www.sciencedirect.com/science/article/pii/S2352771423001805Q feverEmerging diseaseSmall ruminantsSeroepidemiologyZoonosesRisk factors |
| spellingShingle | Danilo Alves de França Filipe Pereira da Silva Dayane da Silva Zanini Lorena Iglesias Laura Portillo Herminia Cortez Alexander Welker Biondo Ana Íris de Lima Duré Marcos Vinicius Ferreira Silva Jorge Miret Helio Langoni Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country One Health Q fever Emerging disease Small ruminants Seroepidemiology Zoonoses Risk factors |
| title | Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country |
| title_full | Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country |
| title_fullStr | Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country |
| title_full_unstemmed | Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country |
| title_short | Coxiella burnetii seroprevalence in sheep herd from Paraguay: First evidence of bacterial circulation in the country |
| title_sort | coxiella burnetii seroprevalence in sheep herd from paraguay first evidence of bacterial circulation in the country |
| topic | Q fever Emerging disease Small ruminants Seroepidemiology Zoonoses Risk factors |
| url | http://www.sciencedirect.com/science/article/pii/S2352771423001805 |
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