Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation

Background: In this study we evaluated the treatment of giant cell tumor (GCT) of long bones using cryosurgery combined with curettage and polymethylmetacrylate (PMMA) cementing. Material and methods: From January 1999 to December 2004, twenty patients (mean age at the time of surgery 29.2 years); 1...

Full description

Bibliographic Details
Main Authors: Mortazavi S.M.J, Moatamedi M, Farzan M, Moghtadaei M
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2005-07-01
Series:Tehran University Medical Journal
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/957.pdf&manuscript_id=957
_version_ 1819181898456367104
author Mortazavi S.M.J
Moatamedi M
Farzan M
Moghtadaei M
author_facet Mortazavi S.M.J
Moatamedi M
Farzan M
Moghtadaei M
author_sort Mortazavi S.M.J
collection DOAJ
description Background: In this study we evaluated the treatment of giant cell tumor (GCT) of long bones using cryosurgery combined with curettage and polymethylmetacrylate (PMMA) cementing. Material and methods: From January 1999 to December 2004, twenty patients (mean age at the time of surgery 29.2 years); 13 females and 7 males; were included in the study. Cortical disruption were presented in 7 patients; 4 with soft tissue extension, but none of them had intra-articular extension of tumor, 3 patients presented with pathologic fracture of distal femoral lesions. These tumors were located in distal femur in 6 patients, proximal tibia in 7, distal radius in 3, proximal femur in 2, and each of proximal humerus and distal ulna in one patient. In each case diagnostic biopsy was done and surgical procedure performed including curettage, power burr of the wall, cryosurgery with liquid nitrogen and finally filling the space with PMMA cementing. The mean follow-up was 34 months (7 to 61 ). Results: During follow-up, we observed one recurrence of GCT of proximal tibia. Secondary Aneurysmal bone cyst was reported at the site of one primary distal femoral lesion, without any finding in favor of a recurrence. Neurapraxia of the proneal nerve was occurred in one patient with proximal tibia tumor improved after 8 months. Conclusion: Cryosurgery combined with power burr and PMMA cementing in the treatment of GCT could be an effective approach in tumor eradication. This method obviates the need for extensive resections and reconstructive procedure.
first_indexed 2024-12-22T22:37:33Z
format Article
id doaj.art-649b7521f4884dc29359c02c117a181a
institution Directory Open Access Journal
issn 1683-1764
1735-7322
language fas
last_indexed 2024-12-22T22:37:33Z
publishDate 2005-07-01
publisher Tehran University of Medical Sciences
record_format Article
series Tehran University Medical Journal
spelling doaj.art-649b7521f4884dc29359c02c117a181a2022-12-21T18:10:17ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222005-07-01634289296Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And CementationMortazavi S.M.JMoatamedi MFarzan MMoghtadaei MBackground: In this study we evaluated the treatment of giant cell tumor (GCT) of long bones using cryosurgery combined with curettage and polymethylmetacrylate (PMMA) cementing. Material and methods: From January 1999 to December 2004, twenty patients (mean age at the time of surgery 29.2 years); 13 females and 7 males; were included in the study. Cortical disruption were presented in 7 patients; 4 with soft tissue extension, but none of them had intra-articular extension of tumor, 3 patients presented with pathologic fracture of distal femoral lesions. These tumors were located in distal femur in 6 patients, proximal tibia in 7, distal radius in 3, proximal femur in 2, and each of proximal humerus and distal ulna in one patient. In each case diagnostic biopsy was done and surgical procedure performed including curettage, power burr of the wall, cryosurgery with liquid nitrogen and finally filling the space with PMMA cementing. The mean follow-up was 34 months (7 to 61 ). Results: During follow-up, we observed one recurrence of GCT of proximal tibia. Secondary Aneurysmal bone cyst was reported at the site of one primary distal femoral lesion, without any finding in favor of a recurrence. Neurapraxia of the proneal nerve was occurred in one patient with proximal tibia tumor improved after 8 months. Conclusion: Cryosurgery combined with power burr and PMMA cementing in the treatment of GCT could be an effective approach in tumor eradication. This method obviates the need for extensive resections and reconstructive procedure.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/957.pdf&manuscript_id=957Giant cell tumorCryosurgeryCementingPower burr
spellingShingle Mortazavi S.M.J
Moatamedi M
Farzan M
Moghtadaei M
Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
Tehran University Medical Journal
Giant cell tumor
Cryosurgery
Cementing
Power burr
title Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
title_full Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
title_fullStr Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
title_full_unstemmed Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
title_short Giant Cell Tumor Of The Long Bones: Results With Combination Of Cryosurgery, Curettage, And Cementation
title_sort giant cell tumor of the long bones results with combination of cryosurgery curettage and cementation
topic Giant cell tumor
Cryosurgery
Cementing
Power burr
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/957.pdf&manuscript_id=957
work_keys_str_mv AT mortazavismj giantcelltumorofthelongbonesresultswithcombinationofcryosurgerycurettageandcementation
AT moatamedim giantcelltumorofthelongbonesresultswithcombinationofcryosurgerycurettageandcementation
AT farzanm giantcelltumorofthelongbonesresultswithcombinationofcryosurgerycurettageandcementation
AT moghtadaeim giantcelltumorofthelongbonesresultswithcombinationofcryosurgerycurettageandcementation