E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice
The use of E-cigarettes has increased despite the unknown long-term effects. Here the authors show that e-cigarette aerosols alter cardiac conduction, repolarization, and autonomic regulation in mice, contingent on the chemical composition of e-liquids and partly through parasympathetic modulation.
Main Authors: | Alex P. Carll, Claudia Arab, Renata Salatini, Meredith D. Miles, Matthew A. Nystoriak, Kyle L. Fulghum, Daniel W. Riggs, Gregg A. Shirk, Whitney S. Theis, Nima Talebi, Aruni Bhatnagar, Daniel J. Conklin |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-33203-1 |
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