Development of non-alcoholic steatohepatitis is associated with gut microbiota but not with oxysterol enzymes CH25H, EBI2, or CYP7B1 in mice

Abstract Liver steatosis is the most frequent liver disorder and its advanced stage, non-alcoholic steatohepatitis (NASH), will soon become the main reason for liver fibrosis and cirrhosis. The “multiple hits hypothesis” suggests that progression from simple steatosis to NASH is triggered by multipl...

Полное описание

Библиографические подробности
Главные авторы: Jacqueline Wyss, Tina Raselli, Annika Wyss, Anja Telzerow, Gerhard Rogler, Niklas Krupka, Bahtiyar Yilmaz, Thomas S. B. Schmidt, Benjamin Misselwitz
Формат: Статья
Язык:English
Опубликовано: BMC 2024-02-01
Серии:BMC Microbiology
Предметы:
Online-ссылка:https://doi.org/10.1186/s12866-024-03195-7