Nuclear genetic regulation of the human mitochondrial transcriptome

Nuclear genetic regulation of the human mitochondrial transcriptome

Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable vari...

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Bibliographic Details
Main Authors: Aminah T Ali, Lena Boehme, Guillermo Carbajosa, Vlad C Seitan, Kerrin S Small, Alan Hodgkinson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
transcriptome
mitochondria
mtRNA
eQTL
RNA sequencing
expression
Online Access:https://elifesciences.org/articles/41927

Internet

https://elifesciences.org/articles/41927

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