Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study

Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study

Parameters of water diffusion in white matter derived from diffusion-weighted imaging (DWI), such as fractional anisotropy (FA), mean, axial, and radial diffusivity (MD, AD, and RD), and more recently, peak width of skeletonized mean diffusivity (PSMD), have been proposed as potential markers of nor...

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Bibliographic Details
Main Authors: Grégory Beaudet, Ami Tsuchida, Laurent Petit, Christophe Tzourio, Svenja Caspers, Jan Schreiber, Zdenka Pausova, Yash Patel, Tomas Paus, Reinhold Schmidt, Lukas Pirpamer, Perminder S. Sachdev, Henry Brodaty, Nicole Kochan, Julian Trollor, Wei Wen, Nicola J. Armstrong, Ian J. Deary, Mark E. Bastin, Joanna M. Wardlaw, Susana Munõz Maniega, A. Veronica Witte, Arno Villringer, Marco Duering, Stéphanie Debette, Bernard Mazoyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Psychiatry
Subjects:
ageing
white matter
neurodegeneration
MRI
diffusion
PSMD
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00342/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2020.00342/full

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