PinX1-Promoted Autophagy Inhibits Cell Proliferation and Induces Cell Apoptosis by Inhibiting the NF-κB/p65 Signaling Pathway in Nasopharyngeal Carcinoma

PinX1-Promoted Autophagy Inhibits Cell Proliferation and Induces Cell Apoptosis by Inhibiting the NF-κB/p65 Signaling Pathway in Nasopharyngeal Carcinoma

Background: The role of Pin2 telomeric repeat factor 1-interacting telomerase inhibitor 1 (PinX1) in tumorigenesis and development has been extensively studied. As we previously demonstrated, PinX1 plays an important role in modulating epithelial-mesenchymal transition (EMT), stemness, cell prolifer...

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Bibliographic Details
Main Authors: Mengxue Yang, Fang Chen, Chaosheng Yu, Zhimou Cai, Qingwen Zhong, Jialian Feng, Guanxue Li, Congxiang Shen, Zhong Wen
Format: Article
Language:English
Published: IMR Press 2023-08-01
Series:Frontiers in Bioscience-Landmark
Subjects:
nasopharyngeal carcinoma
autophagic flux
migration
akt/mtor pathway
Online Access:https://www.imrpress.com/journal/FBL/28/8/10.31083/j.fbl2808170

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