Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China
This study was a cross-sectional case-control study aimed at (1) identifying risk factors contributing to the measles epidemic and (2) evaluating the impacts of measles-containing vaccines (MCVs), with the goal of providing evidence-based recommendations for measles elimination strategies in China....
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| Format: | Article |
| Language: | English |
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Elsevier
2017-09-01
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| Series: | Journal of Infection and Public Health |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S187603411730062X |
| _version_ | 1818008436517896192 |
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| author | Rong-Qiang Zhang Hong-Bing Li Feng-Ying Li Li-Xin Han Yong-Min Xiong |
| author_facet | Rong-Qiang Zhang Hong-Bing Li Feng-Ying Li Li-Xin Han Yong-Min Xiong |
| author_sort | Rong-Qiang Zhang |
| collection | DOAJ |
| description | This study was a cross-sectional case-control study aimed at (1) identifying risk factors contributing to the measles epidemic and (2) evaluating the impacts of measles-containing vaccines (MCVs), with the goal of providing evidence-based recommendations for measles elimination strategies in China. Data on measles cases from 2000 to 2014 were obtained from a passive surveillance system at the Center for Diseases Prevention and Control in Xianyang. The effectiveness of MCVs was evaluated in 357 patients with a vaccination history and 503 healthy randomly selected controls. Patient data were subjected to multivariable logistic regression modeling. From 2005 to 2014, the average incidence of measles in Xianyang was 5.42 cases per 100,000 people. The second MCV dose was highly protective in 8-month-old infants. MCVs in general have been highly protective in 8-month-old infants. Multivariable logistic regression modeling indicated that age (≥2 years vs. <2 years), MCV dose 2 vaccination, and MV vaccination were each independently associated with measles case status. In conclusions: A MCV should be administered on time to all age-eligible children, reproductive-age women, and migrant populations, to maximize herd immunity to measles. Keywords: Epidemiological characteristics, Measles, Vaccination |
| first_indexed | 2024-04-14T05:29:08Z |
| format | Article |
| id | doaj.art-64a519b804a74dd18325082cb53810b0 |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-04-14T05:29:08Z |
| publishDate | 2017-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-64a519b804a74dd18325082cb53810b02022-12-22T02:09:52ZengElsevierJournal of Infection and Public Health1876-03412017-09-01105624629Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, ChinaRong-Qiang Zhang0Hong-Bing Li1Feng-Ying Li2Li-Xin Han3Yong-Min Xiong4School of Public Health, Shaanxi University of Chinese Medicine, Shiji Road, Xianyang, Shaanxi 712046, PR China; Institute of Endemic Diseases of School of Public Health, Health Science Center, Xi’an Jiaotong University; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education; Key Laboratory of Trace Elements and Endemic Diseases of Ministry of Health, Xi’an, Shaanxi 710061, PR ChinaCenter for Disease Control and Prevention of Baoji City, Shaanxi 721006, PR ChinaCenter for Disease Control and Prevention of Xianyang City, Shaanxi 712046, PR ChinaInstitute of Endemic Diseases of School of Public Health, Health Science Center, Xi’an Jiaotong University; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education; Key Laboratory of Trace Elements and Endemic Diseases of Ministry of Health, Xi’an, Shaanxi 710061, PR ChinaInstitute of Endemic Diseases of School of Public Health, Health Science Center, Xi’an Jiaotong University; Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education; Key Laboratory of Trace Elements and Endemic Diseases of Ministry of Health, Xi’an, Shaanxi 710061, PR China; Corresponding author at: School of Public Health, Health Science Center of Xi’an Jiaotong University, No 76 Yanta West Road, Xi’an, Shaanxi 710061, PR China. Fax: +86 29 82655032.This study was a cross-sectional case-control study aimed at (1) identifying risk factors contributing to the measles epidemic and (2) evaluating the impacts of measles-containing vaccines (MCVs), with the goal of providing evidence-based recommendations for measles elimination strategies in China. Data on measles cases from 2000 to 2014 were obtained from a passive surveillance system at the Center for Diseases Prevention and Control in Xianyang. The effectiveness of MCVs was evaluated in 357 patients with a vaccination history and 503 healthy randomly selected controls. Patient data were subjected to multivariable logistic regression modeling. From 2005 to 2014, the average incidence of measles in Xianyang was 5.42 cases per 100,000 people. The second MCV dose was highly protective in 8-month-old infants. MCVs in general have been highly protective in 8-month-old infants. Multivariable logistic regression modeling indicated that age (≥2 years vs. <2 years), MCV dose 2 vaccination, and MV vaccination were each independently associated with measles case status. In conclusions: A MCV should be administered on time to all age-eligible children, reproductive-age women, and migrant populations, to maximize herd immunity to measles. Keywords: Epidemiological characteristics, Measles, Vaccinationhttp://www.sciencedirect.com/science/article/pii/S187603411730062X |
| spellingShingle | Rong-Qiang Zhang Hong-Bing Li Feng-Ying Li Li-Xin Han Yong-Min Xiong Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China Journal of Infection and Public Health |
| title | Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China |
| title_full | Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China |
| title_fullStr | Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China |
| title_full_unstemmed | Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China |
| title_short | Epidemiological characteristics of measles from 2000 to 2014: Results of a measles catch-up vaccination campaign in Xianyang, China |
| title_sort | epidemiological characteristics of measles from 2000 to 2014 results of a measles catch up vaccination campaign in xianyang china |
| url | http://www.sciencedirect.com/science/article/pii/S187603411730062X |
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