Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking

Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking

Abstract G Protein-Coupled Receptors (GPCRs) are integral membrane proteins that have gained considerable attention as drug targets, particularly in cancer treatment. In this study, we explored the capacity of bioactive compounds derived from Gnetum gnemon (GG) for the development of of pharmaceutic...

詳細記述

書誌詳細
主要な著者: Moragot Chatatikun, Nawanwat C. Pattaranggoon, Imran Sama-ae, Onggan Ranteh, Manlika Poolpirom, Oranan Pantanakong, Pitchaporn Chumworadet, Fumitaka Kawakami, Motoki Imai, Aman Tedasen
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2024-10-01
シリーズ:Scientific Reports
主題:
GPCRs
Cancer
ADME
Network pharmacology
Molecular docking
オンライン･アクセス:https://doi.org/10.1038/s41598-024-75240-4

インターネット

https://doi.org/10.1038/s41598-024-75240-4

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