2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes

2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes

Context: 2,3-Butanedione monoxime (BDM), an uncoupler of cardiac contraction, is commonly used in enzymatic dissociations to prevent hypercontraction of cardiomyocytes and in cardioplegic solutions to decrease oxygen demand during surgery. However, BDM affects multiple cellular systems including the...

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Bibliographic Details
Main Authors:	Julio Alvarez-Collazo, Ana Iris López-Medina, Loipa Galán-Martínez, Julio L. Alvarez
Format:	Article
Language:	English
Published:	GarVal Editorial Ltda. 2016-12-01
Series:	Journal of Pharmacy & Pharmacognosy Research
Subjects:	2-3-butanedione monoxime calcium channels cardiomyocytes; myocardial preservation; patch-clamp cardiomyocytes myocardial preservation patch-clamp
Online Access:	http://jppres.com/jppres/pdf/vol4/jppres16.150_4.6.206.pdf

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