Clinical Presentation of Patients with Pituitary Tumour and its Correlation to Magnetic Resonance Imaging: An Observational Study
Introduction: Pituitary tumours are common intracranial tumours affecting mainly the 4th to 7th decade of life. A detailed understanding of these pituitary tumour patients, especially regarding their clinical and MRI profile would help in its early detection.It also help in deciding upon further...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2021-10-01
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| Series: | International Journal of Anatomy Radiology and Surgery |
| Subjects: | |
| Online Access: | http://www.ijars.net/articles/PDF/2703/48451_CE[Ra1]_F(SHU)%20GC(AnK)_PF1(MG_SHU)_PFA(MG_KM)_PN(KM).pdf |
| Summary: | Introduction: Pituitary tumours are common intracranial tumours
affecting mainly the 4th to 7th decade of life. A detailed understanding
of these pituitary tumour patients, especially regarding their clinical
and MRI profile would help in its early detection.It also help in
deciding upon further management (medical or surgical or radiation),
thus helping in improved outcome.
Aim: To find out the common clinical presentations and the MRI
findings of pituitary tumour.
Materials and Methods: A cross-sectional observational study
was carried out among 88 patients admitted with diagnosis
of pituitary tumour in a tertiary care center from 1st June 2018
to 30th September 2019. The study involved initial clinical
assessment followed by MRI brain of all the patients included in
the study. To find out relationship between imaging findings and
clinical symptoms statistical analysis was done.
Results: The most common clinical presentations were headache
in 55 patients (commonly throbbing type in frontal region) and
visual field defects in 52 patients (uni/bitemporal hemianopia).
A 51 (58%) patients had suprasellar extension and 35 (39.8%)
patients had tumour already progressed to parasellar extension
stage at time of detection of adenoma. Most of the patients
detected with pituitary tumours (i.e., 63.6%) had grade two
invasion. Four incidental adenomas were detected and none
of them had parasellar extension. Among 35 patients with
parasellar extension, 27 (77.1%) patients had visual disturbance.
In 45 (51.1%) patients without parasellar extension had no sellar
floor involvement. Visual disturbance was significantly associated
with the parasellar extension of the tumour.
Conclusion: Headache and visual field defects were the most
common clinical presentation among pituitary tumour patients.
Patients with tumours having parasellar extension are more
likely to have visual disturbance than with patients having only
suprasellar extension. Radiologically, pituitary tumours tend to
expand only into suprasellar area, then it involves the parasellar
area, followed by sellar floor which occurred last. |
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| ISSN: | 2277-8543 2455-6874 |