Challenges in Matrix Metalloproteinases Inhibition

Challenges in Matrix Metalloproteinases Inhibition

Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need to develop inhibitors for these enzymes in orde...

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Bibliographic Details
Main Authors: Helena Laronha, Inês Carpinteiro, Jaime Portugal, Ana Azul, Mário Polido, Krasimira T. Petrova, Madalena Salema-Oom, Jorge Caldeira
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
matrix metalloproteinases
TIMP
synthetic inhibitors
Online Access:https://www.mdpi.com/2218-273X/10/5/717

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