The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture
(1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and periapical periodontium, as well as the failure of endodontic treatment. The subsequent root canal treatment is not able to remove all the pathogen...
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| Format: | Article |
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MDPI AG
2022-01-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/2/158 |
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| author | Matej Rosa Yuliya Morozova Roman Moštěk Pavel Holík Lucia Somolová Barbora Novotná Soňa Zábojníková Kateřina Bogdanová Kateřina Langová Iva Voborná Lenka Pospíšilová Josef Paul Kovařík |
| author_facet | Matej Rosa Yuliya Morozova Roman Moštěk Pavel Holík Lucia Somolová Barbora Novotná Soňa Zábojníková Kateřina Bogdanová Kateřina Langová Iva Voborná Lenka Pospíšilová Josef Paul Kovařík |
| author_sort | Matej Rosa |
| collection | DOAJ |
| description | (1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and periapical periodontium, as well as the failure of endodontic treatment. The subsequent root canal treatment is not able to remove all the pathogens, and a small number of viable bacteria remain in the dentine tubules, which must be sealed by endodontic sealers. These sealers should have at least a bacteriostatic effect to prevent the remaining bacteria from reproducing. The aim of this study is to compare the short-term antibacterial activity of three endodontic sealers based on poly-epoxy resin, zinc oxide-eugenol and calcium silicate with a calcium hydroxide-based sealer. Calcium hydroxide is used as temporary intracanal medicament and, thus, should show significant antibacterial activity. (2) Methods: A total of 25 bovine dentine samples infected with <i>Enterococcus faecalis</i> were used in this study. After the sealer placement and a 24 h incubation period, the root canal walls were scraped, and the suspension of dentine fillings was used for a semi-quantitative evaluation of microbial growth. (3) Results: The poly-epoxide resin-based sealer ADSeal™ showed significant antibacterial properties. (4) Conclusions: The highest antibacterial activity was shown in poly-epoxide resin-based sealer group, followed by the zinc oxide-eugenol-based sealer and calcium silicate-based sealer. |
| first_indexed | 2024-03-09T21:35:21Z |
| format | Article |
| id | doaj.art-64ad8be5d91f484aaa46179870636d49 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T21:35:21Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-64ad8be5d91f484aaa46179870636d492023-11-23T20:45:00ZengMDPI AGLife2075-17292022-01-0112215810.3390/life12020158The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial CultureMatej Rosa0Yuliya Morozova1Roman Moštěk2Pavel Holík3Lucia Somolová4Barbora Novotná5Soňa Zábojníková6Kateřina Bogdanová7Kateřina Langová8Iva Voborná9Lenka Pospíšilová10Josef Paul Kovařík11Institute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicDepartment of Microbiology, University Hospital Olomouc, I. P. Pavlova 6, 779 00 Olomouc, Czech RepublicDepartment of Medical Biophysics, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech RepublicInstitute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, 775 15 Olomouc, Czech Republic(1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and periapical periodontium, as well as the failure of endodontic treatment. The subsequent root canal treatment is not able to remove all the pathogens, and a small number of viable bacteria remain in the dentine tubules, which must be sealed by endodontic sealers. These sealers should have at least a bacteriostatic effect to prevent the remaining bacteria from reproducing. The aim of this study is to compare the short-term antibacterial activity of three endodontic sealers based on poly-epoxy resin, zinc oxide-eugenol and calcium silicate with a calcium hydroxide-based sealer. Calcium hydroxide is used as temporary intracanal medicament and, thus, should show significant antibacterial activity. (2) Methods: A total of 25 bovine dentine samples infected with <i>Enterococcus faecalis</i> were used in this study. After the sealer placement and a 24 h incubation period, the root canal walls were scraped, and the suspension of dentine fillings was used for a semi-quantitative evaluation of microbial growth. (3) Results: The poly-epoxide resin-based sealer ADSeal™ showed significant antibacterial properties. (4) Conclusions: The highest antibacterial activity was shown in poly-epoxide resin-based sealer group, followed by the zinc oxide-eugenol-based sealer and calcium silicate-based sealer.https://www.mdpi.com/2075-1729/12/2/158antibacterialantimicrobialendodonticsealerpoly-epoxy resinzinc oxide-eugenol |
| spellingShingle | Matej Rosa Yuliya Morozova Roman Moštěk Pavel Holík Lucia Somolová Barbora Novotná Soňa Zábojníková Kateřina Bogdanová Kateřina Langová Iva Voborná Lenka Pospíšilová Josef Paul Kovařík The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture Life antibacterial antimicrobial endodontic sealer poly-epoxy resin zinc oxide-eugenol |
| title | The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture |
| title_full | The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture |
| title_fullStr | The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture |
| title_full_unstemmed | The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture |
| title_short | The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against <i>Enterococcus faecalis</i> Bacterial Culture |
| title_sort | short term antibacterial activity of three selected endodontic sealers against i enterococcus faecalis i bacterial culture |
| topic | antibacterial antimicrobial endodontic sealer poly-epoxy resin zinc oxide-eugenol |
| url | https://www.mdpi.com/2075-1729/12/2/158 |
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