Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients

Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients and compare it with the same age and sex matched healthy volunteers. Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were include...

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Main Authors: Meltem Vural, Zeynep Topkarcı, Sedef Ersoy, Belgin Erhan, Berrin Gündüz
Format: Article
Language:English
Published: Galenos Yayinevi 2014-12-01
Series:Türk Osteoporoz Dergisi
Subjects:
Online Access:http://www.turkosteoporozdergisi.org/article_7593/Evaluation-Of-Serum-25-hydroxy-Vitamin-D-Levels-In-Premenapousal-Psoriasis-Patients
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author Meltem Vural
Zeynep Topkarcı
Sedef Ersoy
Belgin Erhan
Berrin Gündüz
author_facet Meltem Vural
Zeynep Topkarcı
Sedef Ersoy
Belgin Erhan
Berrin Gündüz
author_sort Meltem Vural
collection DOAJ
description Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients and compare it with the same age and sex matched healthy volunteers. Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were included in the study. Serum 25-hydroxy vitamin D levels were compared between the two groups; also the relationship of disease activity and 25-hydroxy Vitamin D levels were examined in patients with psoriasis. Probability values of <0.05 were considered as statistically significant. Results: The mean age of patients with psoriasis and control groups were not statistically different (p>0.05). In addition, the mean 25-hydroxy vitamin D levels were not significantly different among the two groups (p>0.05). 25-hydroxy vitamin D levels were no significantly different in patients with and without psoriatic arthritis (p>0.05). No significant correlation was found between psoriasis area severity index PASI values, age or 25-hydroxy vitamin D levels (p>0.05). Conclusion: The low levels of vitamin D in population is reported to be common. In our study, similar low vitamin D levels were found in healthy volunteers and premenopausal psoriasis patients. Serum 25-hydroxy vitamin D levels were not correlated with disease activity in patients with psoriasis. Correlation between psoriasis, disease activity and vitamin D levels should be investigated in larger populations. (Turkish Journal of Osteoporosis 2014;20: 93-7)
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spelling doaj.art-64b09911432f4979b5200836656c176f2023-02-15T16:20:20ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532014-12-012039397Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis PatientsMeltem Vural0 Zeynep Topkarcı1 Sedef Ersoy2Belgin Erhan3Berrin Gündüz4İstanbul Fizik Tedavi Rehabilitasyon Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul, Türkiye(1)Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Dermatoloji Kliniği, İstanbul, TürkiyeBakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul, Türkiyestanbul Aydın Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, İstanbul, Türkiyeİstanbul Fizik Tedavi Rehabilitasyon Eğitim ve Araştırma Hastanesi, Fizik Tedavi ve Rehabilitasyon Kliniği, İstanbul, Türkiye(1)Objective: To investigate the serum 25-hydroxy vitamin D levels in systemic treatment planned premenopausal psoriasis patients and compare it with the same age and sex matched healthy volunteers. Materials and Methods: Forty-one psoriasis patients and 57 healthy controls (total of 98) were included in the study. Serum 25-hydroxy vitamin D levels were compared between the two groups; also the relationship of disease activity and 25-hydroxy Vitamin D levels were examined in patients with psoriasis. Probability values of <0.05 were considered as statistically significant. Results: The mean age of patients with psoriasis and control groups were not statistically different (p>0.05). In addition, the mean 25-hydroxy vitamin D levels were not significantly different among the two groups (p>0.05). 25-hydroxy vitamin D levels were no significantly different in patients with and without psoriatic arthritis (p>0.05). No significant correlation was found between psoriasis area severity index PASI values, age or 25-hydroxy vitamin D levels (p>0.05). Conclusion: The low levels of vitamin D in population is reported to be common. In our study, similar low vitamin D levels were found in healthy volunteers and premenopausal psoriasis patients. Serum 25-hydroxy vitamin D levels were not correlated with disease activity in patients with psoriasis. Correlation between psoriasis, disease activity and vitamin D levels should be investigated in larger populations. (Turkish Journal of Osteoporosis 2014;20: 93-7)http://www.turkosteoporozdergisi.org/article_7593/Evaluation-Of-Serum-25-hydroxy-Vitamin-D-Levels-In-Premenapousal-Psoriasis-PatientsPsoriasis25-hydroxyvitamin Dpsoriasis area severity index
spellingShingle Meltem Vural
Zeynep Topkarcı
Sedef Ersoy
Belgin Erhan
Berrin Gündüz
Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
Türk Osteoporoz Dergisi
Psoriasis
25-hydroxyvitamin D
psoriasis area severity index
title Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
title_full Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
title_fullStr Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
title_full_unstemmed Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
title_short Evaluation of Serum 25-Hydroxy Vitamin D Levels in Premenapousal Psoriasis Patients
title_sort evaluation of serum 25 hydroxy vitamin d levels in premenapousal psoriasis patients
topic Psoriasis
25-hydroxyvitamin D
psoriasis area severity index
url http://www.turkosteoporozdergisi.org/article_7593/Evaluation-Of-Serum-25-hydroxy-Vitamin-D-Levels-In-Premenapousal-Psoriasis-Patients
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AT zeyneptopkarcı evaluationofserum25hydroxyvitamindlevelsinpremenapousalpsoriasispatients
AT sedefersoy evaluationofserum25hydroxyvitamindlevelsinpremenapousalpsoriasispatients
AT belginerhan evaluationofserum25hydroxyvitamindlevelsinpremenapousalpsoriasispatients
AT berringunduz evaluationofserum25hydroxyvitamindlevelsinpremenapousalpsoriasispatients