Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients
Introduction Prostate-specific antigen (PSA) is a biomarker commonly used for detection of prostate cancer. Its viability as a marker for diagnosis of chronic renal failure (CRF) in predialysis patients was investigated. Methods Sera from 230 patients with CRF were analyzed by enzyme-linked immunos...
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2021-04-01
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| Series: | Asian Journal of Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1729346 |
| _version_ | 1819322938691682304 |
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| author | Ali Abdul Hussein S Al-Janabi |
| author_facet | Ali Abdul Hussein S Al-Janabi |
| author_sort | Ali Abdul Hussein S Al-Janabi |
| collection | DOAJ |
| description | Introduction Prostate-specific antigen (PSA) is a biomarker commonly used for detection of prostate cancer. Its viability as a marker for diagnosis of chronic renal failure (CRF) in predialysis patients was investigated.
Methods Sera from 230 patients with CRF were analyzed by enzyme-linked immunosorbent assay (ELISA) for determining total PSA (tPSA) levels before hemodialysis.
Results Of the patients investigated, 98.69% had a normal PSA level with a value less than 4 ng/mL. Three elderly men with both kidney failure showed a moderate elevation of PSA level.
Conclusion PSA is considered a nonsignificant indicator for diagnosis of CRF. |
| first_indexed | 2024-12-24T11:59:19Z |
| format | Article |
| id | doaj.art-64b1acbe91b44146a7edd0b42897da31 |
| institution | Directory Open Access Journal |
| issn | 2454-6798 2455-4618 |
| language | English |
| last_indexed | 2024-12-24T11:59:19Z |
| publishDate | 2021-04-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Asian Journal of Oncology |
| spelling | doaj.art-64b1acbe91b44146a7edd0b42897da312022-12-21T16:56:24ZengThieme Medical Publishers, Inc.Asian Journal of Oncology2454-67982455-46182021-04-01070208208410.1055/s-0041-1729346Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis PatientsAli Abdul Hussein S Al-Janabi0Department of Microbiology, College of Medicine, University of Karbala, Karbala, IraqIntroduction Prostate-specific antigen (PSA) is a biomarker commonly used for detection of prostate cancer. Its viability as a marker for diagnosis of chronic renal failure (CRF) in predialysis patients was investigated. Methods Sera from 230 patients with CRF were analyzed by enzyme-linked immunosorbent assay (ELISA) for determining total PSA (tPSA) levels before hemodialysis. Results Of the patients investigated, 98.69% had a normal PSA level with a value less than 4 ng/mL. Three elderly men with both kidney failure showed a moderate elevation of PSA level. Conclusion PSA is considered a nonsignificant indicator for diagnosis of CRF.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1729346psachronic kidney failureprostaterenal dialysis |
| spellingShingle | Ali Abdul Hussein S Al-Janabi Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients Asian Journal of Oncology psa chronic kidney failure prostate renal dialysis |
| title | Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients |
| title_full | Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients |
| title_fullStr | Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients |
| title_full_unstemmed | Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients |
| title_short | Prostate-Specific Antigen: From Promising to Disappointment Tool for Diagnosis of Chronic Renal Failure in Predialysis Patients |
| title_sort | prostate specific antigen from promising to disappointment tool for diagnosis of chronic renal failure in predialysis patients |
| topic | psa chronic kidney failure prostate renal dialysis |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1729346 |
| work_keys_str_mv | AT aliabdulhusseinsaljanabi prostatespecificantigenfrompromisingtodisappointmenttoolfordiagnosisofchronicrenalfailureinpredialysispatients |