Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain
Propofol is commonly used intravenous anesthesia induction drug but it causes ache upon use, many methods with different results, have been suggested to prevent this pain, the current research was concluded in order to investigate the impact of lidocaine, ketamine in reducing the ache on giving intr...
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| Format: | Article |
| Language: | English |
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Sulaimani Polytechnic University
2019-12-01
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| Series: | Kurdistan Journal of Applied Research |
| Subjects: | |
| Online Access: | https://kjar.spu.edu.iq/index.php/kjar/article/view/418 |
| _version_ | 1797197671230865408 |
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| author | Amir Murad Khudadad Boujan Nashmeel fazeel Kareem Amanj A. Marouf Saman Abdullah Ahmed Fahmi Salah Qadir Mahmood |
| author_facet | Amir Murad Khudadad Boujan Nashmeel fazeel Kareem Amanj A. Marouf Saman Abdullah Ahmed Fahmi Salah Qadir Mahmood |
| author_sort | Amir Murad Khudadad Boujan |
| collection | DOAJ |
| description | Propofol is commonly used intravenous anesthesia induction drug but it causes ache upon use, many methods with different results, have been suggested to prevent this pain, the current research was concluded in order to investigate the impact of lidocaine, ketamine in reducing the ache on giving intravenous propofol. This study is randomized controlled clinical trial lasting from June 2015 to November 2015 during which 107 consenting (ASA1 and ASA2) patients were prepared for elective operation with general anesthesia. They randomly split to three subgroups, A cannula (size20) used in the dorsum hand veins, standard monitor was established patients received either 2mL (40 mg) of lidocaine or 2mL (20mg) of ketamine and 2 mL of saline 1 min before injection 2.5 milligram per kilogram propofol. ache severity observed by using four number pain scale, zero = none, one= mild pain, two = moderate pain, and three = intense pain. Atracurium used for indotracheal intubation, isoflurane and fentanyl for anesthesia maintenance. There were no variations between the study groups regarding ASA status, Sex, age. The incidence of ache when injecting propofol were observed in the normal saline group was 86.5% and it was more than ketamine group 0% and lidocaine group 20% (p=0.0002). In the normal saline pretreatment group 8.1% of the patient experienced severe pain, compared with 0% in the lidocaine and ketamine. It can be concluded that intravenous ketamine and lidocaine were equally effective in preventing Ache during propofol injection.
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| first_indexed | 2024-03-07T14:10:42Z |
| format | Article |
| id | doaj.art-64b88d54fd4f4480b51e168c7a2b0f76 |
| institution | Directory Open Access Journal |
| issn | 2411-7684 2411-7706 |
| language | English |
| last_indexed | 2024-04-24T06:47:40Z |
| publishDate | 2019-12-01 |
| publisher | Sulaimani Polytechnic University |
| record_format | Article |
| series | Kurdistan Journal of Applied Research |
| spelling | doaj.art-64b88d54fd4f4480b51e168c7a2b0f762024-04-22T17:19:19ZengSulaimani Polytechnic UniversityKurdistan Journal of Applied Research2411-76842411-77062019-12-0110.24017/science.2019.ICHMS.25418Lidocaine Versus Ketamine Pretreatment on Propofol Injection PainAmir Murad Khudadad Boujan0Nashmeel fazeel Kareem1Amanj A. Marouf2Saman Abdullah Ahmed Fahmi3Salah Qadir Mahmood4Surgical department, College of Medicine, University of Sulaimani, Sulaimani, IraqAnesthesia department, Sulaimani Teaching Hospital, Sulaimani, IraqSurgical department, College of Medicine, University of Sulaimani, Sulaimani, IraqAnesthesia department, Sulaimani Teaching Hospital, Sulaimani, IraqRadiation department, Sulaimani Technical Institute, Sulaimani Polytechnic University, Sulaimani, IraqPropofol is commonly used intravenous anesthesia induction drug but it causes ache upon use, many methods with different results, have been suggested to prevent this pain, the current research was concluded in order to investigate the impact of lidocaine, ketamine in reducing the ache on giving intravenous propofol. This study is randomized controlled clinical trial lasting from June 2015 to November 2015 during which 107 consenting (ASA1 and ASA2) patients were prepared for elective operation with general anesthesia. They randomly split to three subgroups, A cannula (size20) used in the dorsum hand veins, standard monitor was established patients received either 2mL (40 mg) of lidocaine or 2mL (20mg) of ketamine and 2 mL of saline 1 min before injection 2.5 milligram per kilogram propofol. ache severity observed by using four number pain scale, zero = none, one= mild pain, two = moderate pain, and three = intense pain. Atracurium used for indotracheal intubation, isoflurane and fentanyl for anesthesia maintenance. There were no variations between the study groups regarding ASA status, Sex, age. The incidence of ache when injecting propofol were observed in the normal saline group was 86.5% and it was more than ketamine group 0% and lidocaine group 20% (p=0.0002). In the normal saline pretreatment group 8.1% of the patient experienced severe pain, compared with 0% in the lidocaine and ketamine. It can be concluded that intravenous ketamine and lidocaine were equally effective in preventing Ache during propofol injection. https://kjar.spu.edu.iq/index.php/kjar/article/view/418propofol, pain, lidocaine, Ketamine. |
| spellingShingle | Amir Murad Khudadad Boujan Nashmeel fazeel Kareem Amanj A. Marouf Saman Abdullah Ahmed Fahmi Salah Qadir Mahmood Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain Kurdistan Journal of Applied Research propofol, pain, lidocaine, Ketamine. |
| title | Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain |
| title_full | Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain |
| title_fullStr | Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain |
| title_full_unstemmed | Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain |
| title_short | Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain |
| title_sort | lidocaine versus ketamine pretreatment on propofol injection pain |
| topic | propofol, pain, lidocaine, Ketamine. |
| url | https://kjar.spu.edu.iq/index.php/kjar/article/view/418 |
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