Notch hyper-activation drives trans-differentiation of hESC-derived endothelium

Notch hyper-activation drives trans-differentiation of hESC-derived endothelium

During development, endothelial cells (EC) display tissue-specific attributes that are unique to each vascular bed, as well as generic signaling mechanisms that are broadly applied to create a patent circulatory system. We have previously utilized human embryonic stem cells (hESC) to generate tissue...

Full description

Bibliographic Details
Main Authors: David Reichman, Limor Man, Laura Park, Raphael Lis, Jeannine Gerhardt, Zev Rosenwaks, Daylon James
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116301209

Similar Items

Similar Items