Miliary pulmonary cryptococcosis

A 32-year-old HIV positive male presents with fevers and a non-productive cough. Initial X-ray and subsequent computerised tomography of the chest shows a bilateral miliary pattern of pulmonary infiltration highly suggestive of disseminated tuberculosis. However subsequent results were consistent wi...

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Main Authors: Shane Kelly, Deborah Marriott
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Medical Mycology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753914000372
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author Shane Kelly
Deborah Marriott
author_facet Shane Kelly
Deborah Marriott
author_sort Shane Kelly
collection DOAJ
description A 32-year-old HIV positive male presents with fevers and a non-productive cough. Initial X-ray and subsequent computerised tomography of the chest shows a bilateral miliary pattern of pulmonary infiltration highly suggestive of disseminated tuberculosis. However subsequent results were consistent with disseminated cryptococcosis, including pulmonary involvement, with cryptococcus identified on transbronchial tissue biopsy, and on blood and cerebrospinal fluid cultures. Imaging features of pulmonary cryptococcosis are generally of well-defined pleural-based nodules and less commonly alveolar infiltrates, lymphadenopathy, pleural effusions or cavitating lesions. Miliary pulmonary infiltrates are an exceptionally rare presentation.
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spelling doaj.art-64bb7092be994d0c969b5c783da52bc22022-12-22T01:12:08ZengElsevierMedical Mycology Case Reports2211-75392014-10-016C222410.1016/j.mmcr.2014.08.004Miliary pulmonary cryptococcosisShane Kelly0Deborah Marriott1Department of Immunology and Infectious Diseases, IBAC, St Vincent’s Hospital, Darlinghurst, Sydney 2010, AustraliaDepartment of Immunology and Infectious Diseases, IBAC, St Vincent’s Hospital, Darlinghurst, Sydney 2010, AustraliaA 32-year-old HIV positive male presents with fevers and a non-productive cough. Initial X-ray and subsequent computerised tomography of the chest shows a bilateral miliary pattern of pulmonary infiltration highly suggestive of disseminated tuberculosis. However subsequent results were consistent with disseminated cryptococcosis, including pulmonary involvement, with cryptococcus identified on transbronchial tissue biopsy, and on blood and cerebrospinal fluid cultures. Imaging features of pulmonary cryptococcosis are generally of well-defined pleural-based nodules and less commonly alveolar infiltrates, lymphadenopathy, pleural effusions or cavitating lesions. Miliary pulmonary infiltrates are an exceptionally rare presentation.http://www.sciencedirect.com/science/article/pii/S2211753914000372CryptococcusHIVAIDSMiliaryTuberculosisPulmonary
spellingShingle Shane Kelly
Deborah Marriott
Miliary pulmonary cryptococcosis
Medical Mycology Case Reports
Cryptococcus
HIV
AIDS
Miliary
Tuberculosis
Pulmonary
title Miliary pulmonary cryptococcosis
title_full Miliary pulmonary cryptococcosis
title_fullStr Miliary pulmonary cryptococcosis
title_full_unstemmed Miliary pulmonary cryptococcosis
title_short Miliary pulmonary cryptococcosis
title_sort miliary pulmonary cryptococcosis
topic Cryptococcus
HIV
AIDS
Miliary
Tuberculosis
Pulmonary
url http://www.sciencedirect.com/science/article/pii/S2211753914000372
work_keys_str_mv AT shanekelly miliarypulmonarycryptococcosis
AT deborahmarriott miliarypulmonarycryptococcosis