Short‐and long‐term administration of imeglimin counters cardiorenal dysfunction in a rat model of metabolic syndrome

Short‐and long‐term administration of imeglimin counters cardiorenal dysfunction in a rat model of metabolic syndrome

Abstract Introduction Imeglimin, a glucose‐lowering agent targeting mitochondrial bioenergetics, decreases reactive oxygen species (ROS) overproduction and improves glucose homeostasis. We investigated whether this is associated with protective effects on metabolic syndrome‐related left ventricular...

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Bibliographic Details
Main Authors: Marianne Lachaux, Matthieu Soulié, Mouad Hamzaoui, Anaëlle Bailly, Lionel Nicol, Isabelle Rémy‐Jouet, Sylvanie Renet, Cathy Vendeville, Pascale Gluais‐Dagorn, Sophie Hallakou‐Bozec, Christelle Monteil, Vincent Richard, Paul Mulder
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Endocrinology, Diabetes & Metabolism
Subjects:
cardiomyopathy
imeglimin
rat
type‐2 diabetes
Online Access:https://doi.org/10.1002/edm2.128

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