Synthesis of Aliphatic Polyanhydrides with Controllable and Reproducible Molecular Weight

Synthesis of Aliphatic Polyanhydrides with Controllable and Reproducible Molecular Weight

Polyanhydrides have been synthesized for decades by melt-polycondensation of diacid monomers and 5 to >10 times mole excess acetic anhydride to diacid monomers to form polymers with a polydispersity ranging from 2.5 to 6 and low reproducibility. Hydrophobic segments in polyanhydrides are benefici...

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Bibliographic Details
Main Authors: Radhakanta Ghosh, Yuvaraj Arun, Peter Siman, Abraham J. Domb
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceutics
Subjects:
polyanhydrides
controlled molecular weight
melt polycondensation
drug delivery
Online Access:https://www.mdpi.com/1999-4923/14/7/1403

Internet

https://www.mdpi.com/1999-4923/14/7/1403

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