The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study
This study investigated the impact of Aloe barbadensis Miller (Aloe vera) juice with acemannan on postprandial metabolic markers, antioxidant status, inflammatory responses, and appetite in overweight/obese men following high-fat (HF) meal consumption. In a randomized crossover trial with 16 partici...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464624000173 |
| _version_ | 1797311582331469824 |
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| author | Thavaree Thilavech Siriwan Chumroenvidhayakul Charoonsri Chusak Pasutha Thunyakitpisal Sirichai Adisakwattana |
| author_facet | Thavaree Thilavech Siriwan Chumroenvidhayakul Charoonsri Chusak Pasutha Thunyakitpisal Sirichai Adisakwattana |
| author_sort | Thavaree Thilavech |
| collection | DOAJ |
| description | This study investigated the impact of Aloe barbadensis Miller (Aloe vera) juice with acemannan on postprandial metabolic markers, antioxidant status, inflammatory responses, and appetite in overweight/obese men following high-fat (HF) meal consumption. In a randomized crossover trial with 16 participants, four meal conditions were tested: (1) HF meal, (2) HF meal with A. vera juice (350 mL), (3) HF meal with A. vera juice plus 0.5 g acemannan, and (4) HF meal with A. vera juice plus 1 g acemannan. Enriching A. vera juice with 1 g acemannan significantly reduced postprandial serum triglycerides, and free fatty acids after the HF meal (p < 0.05). Supplementing the HF meal with A. vera juice and acemannan suppressed postprandial glucose, enhanced postprandial antioxidant capacity and reduced tumor necrosis factor-α levels at 6 h (p < 0.05). Notably, the high-concentration acemannan positively influenced appetite by increasing fullness and decreasing hunger ratings. These findings suggest that acemannan enhances A. vera juice benefits in mitigating postprandial dysmetabolism. |
| first_indexed | 2024-03-08T02:02:09Z |
| format | Article |
| id | doaj.art-64c064fb89f3414fa019113ac404cdc2 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-03-08T02:02:09Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-64c064fb89f3414fa019113ac404cdc22024-02-14T05:14:28ZengElsevierJournal of Functional Foods1756-46462024-02-01113106015The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled studyThavaree Thilavech0Siriwan Chumroenvidhayakul1Charoonsri Chusak2Pasutha Thunyakitpisal3Sirichai Adisakwattana4Department of Food Chemistry, Faculty of Pharmacy, Mahidol University, Bangkok 10400, ThailandCenter of Excellence in Phytochemical and Functional Food for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandCenter of Excellence in Phytochemical and Functional Food for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, ThailandResearch Unit of Herbal Medicine, Biomaterial and Material for Dental Treatment, Department of Anatomy, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand; Institute of Dentistry, Suranaree University of Technology, Nakhon Ratchasima 3000, Thailand; Corresponding authors at: Institute of Dentistry, Suranaree University of Technology, Nakhon Ratchasima, Thailand (P. Thunyakitpisal). Phytochemical and Functional Food Research Unit for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Science, Chulalongkorn University, Bangkok, Thailand (S. Adisakwattana).Center of Excellence in Phytochemical and Functional Food for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand; Corresponding authors at: Institute of Dentistry, Suranaree University of Technology, Nakhon Ratchasima, Thailand (P. Thunyakitpisal). Phytochemical and Functional Food Research Unit for Clinical Nutrition, Department of Nutrition and Dietetics, Faculty of Allied Health Science, Chulalongkorn University, Bangkok, Thailand (S. Adisakwattana).This study investigated the impact of Aloe barbadensis Miller (Aloe vera) juice with acemannan on postprandial metabolic markers, antioxidant status, inflammatory responses, and appetite in overweight/obese men following high-fat (HF) meal consumption. In a randomized crossover trial with 16 participants, four meal conditions were tested: (1) HF meal, (2) HF meal with A. vera juice (350 mL), (3) HF meal with A. vera juice plus 0.5 g acemannan, and (4) HF meal with A. vera juice plus 1 g acemannan. Enriching A. vera juice with 1 g acemannan significantly reduced postprandial serum triglycerides, and free fatty acids after the HF meal (p < 0.05). Supplementing the HF meal with A. vera juice and acemannan suppressed postprandial glucose, enhanced postprandial antioxidant capacity and reduced tumor necrosis factor-α levels at 6 h (p < 0.05). Notably, the high-concentration acemannan positively influenced appetite by increasing fullness and decreasing hunger ratings. These findings suggest that acemannan enhances A. vera juice benefits in mitigating postprandial dysmetabolism.http://www.sciencedirect.com/science/article/pii/S1756464624000173AcemannanAloe veraHigh-fat dietPostprandial lipemiaAntioxidantInflammation |
| spellingShingle | Thavaree Thilavech Siriwan Chumroenvidhayakul Charoonsri Chusak Pasutha Thunyakitpisal Sirichai Adisakwattana The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study Journal of Functional Foods Acemannan Aloe vera High-fat diet Postprandial lipemia Antioxidant Inflammation |
| title | The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study |
| title_full | The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study |
| title_fullStr | The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study |
| title_full_unstemmed | The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study |
| title_short | The effect of Aloe vera juice and acemannan on postprandial lipemic, antioxidant, and inflammatory response in high-fat meal fed overweight/obese men: A randomized crossover-controlled study |
| title_sort | effect of aloe vera juice and acemannan on postprandial lipemic antioxidant and inflammatory response in high fat meal fed overweight obese men a randomized crossover controlled study |
| topic | Acemannan Aloe vera High-fat diet Postprandial lipemia Antioxidant Inflammation |
| url | http://www.sciencedirect.com/science/article/pii/S1756464624000173 |
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