Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention
Introduction: Promising Web-based interventions for smokeless tobacco cessation have emerged. We describe a randomized controlled trial (RCT) testing the relative benefits of adding the nicotine lozenge as an adjunct to the MyLastDip Web-based smokeless tobacco cessation intervention. Methods: 407 s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-03-01
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| Series: | Internet Interventions |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214782914000414 |
| _version_ | 1818333072681074688 |
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| author | Brian G. Danaher Herbert H. Severson Ryann Crowley Nora van Meter Milagra S. Tyler Chris Widdop Edward Lichtenstein Jon O. Ebbert |
| author_facet | Brian G. Danaher Herbert H. Severson Ryann Crowley Nora van Meter Milagra S. Tyler Chris Widdop Edward Lichtenstein Jon O. Ebbert |
| author_sort | Brian G. Danaher |
| collection | DOAJ |
| description | Introduction: Promising Web-based interventions for smokeless tobacco cessation have emerged. We describe a randomized controlled trial (RCT) testing the relative benefits of adding the nicotine lozenge as an adjunct to the MyLastDip Web-based smokeless tobacco cessation intervention.
Methods: 407 smokeless tobacco users who wanted to quit were recruited, screened online, and randomly assigned to one of two conditions: (a) the interactive MyLastDip Web-based intervention (Web Only; n = 202), or (b) the website plus the offer of nicotine lozenges (Web + Lozenge; n = 205). MyLastDip program content is grouped according to three sequential frames: preparing to quit, quitting, and staying quit. If a participant reported a lapse then the program would provide tailored content on lessons learned and starting over (“retooling”). The primary outcome was 7-day point prevalence tobacco abstinence measured at follow-up assessments that occurred 3 months and 6 months post-enrollment.
Results: Assessment completion rates were 71.5% at 3 months, 72.9% at 6 months, and 65.1% for both 3 and 6 months, and did not differ by condition. Using Intent to Treat analyses, the Web + Lozenge condition was associated with a significantly higher 7-day point prevalence tobacco abstinence rate than the Web Only condition at 3 months (43.4% vs. 29.7%, p = .004), at the combined 3 and 6 month assessment of repeated point prevalence (35.6% vs. 23.3%, p = .007), but not at 6 months (44.4% vs. 35.1%, p = .057). Similar results were obtained for smokeless tobacco abstinence. Participants reported being satisfied with their programs and the Web + Lozenge condition participants visited the MyLastDip program more often (p < .001). A composite engagement measure of the number and duration of program visits was positively related to 6-month tobacco abstinence (p = .009).
Conclusions: Consistent with previous research, the MyLastDip Web-based tobacco cessation intervention encouraged long-term levels of tobacco and smokeless tobacco abstinence. The addition of nicotine lozenges significantly improved both participant engagement and self-reported 7-day point prevalence tobacco abstinence at 3 months and when considering 3- and 6-month repeated point prevalence tobacco abstinence. |
| first_indexed | 2024-12-13T13:45:50Z |
| format | Article |
| id | doaj.art-64c58ddfb8684329a6b658869e3eeb78 |
| institution | Directory Open Access Journal |
| issn | 2214-7829 |
| language | English |
| last_indexed | 2024-12-13T13:45:50Z |
| publishDate | 2015-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Internet Interventions |
| spelling | doaj.art-64c58ddfb8684329a6b658869e3eeb782022-12-21T23:43:27ZengElsevierInternet Interventions2214-78292015-03-0121697610.1016/j.invent.2014.12.004Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation interventionBrian G. Danaher0Herbert H. Severson1Ryann Crowley2Nora van Meter3Milagra S. Tyler4Chris Widdop5Edward Lichtenstein6Jon O. Ebbert7Oregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAOregon Research Institute, Eugene, OR, USAMayo Clinic, Rochester, MN, USAIntroduction: Promising Web-based interventions for smokeless tobacco cessation have emerged. We describe a randomized controlled trial (RCT) testing the relative benefits of adding the nicotine lozenge as an adjunct to the MyLastDip Web-based smokeless tobacco cessation intervention. Methods: 407 smokeless tobacco users who wanted to quit were recruited, screened online, and randomly assigned to one of two conditions: (a) the interactive MyLastDip Web-based intervention (Web Only; n = 202), or (b) the website plus the offer of nicotine lozenges (Web + Lozenge; n = 205). MyLastDip program content is grouped according to three sequential frames: preparing to quit, quitting, and staying quit. If a participant reported a lapse then the program would provide tailored content on lessons learned and starting over (“retooling”). The primary outcome was 7-day point prevalence tobacco abstinence measured at follow-up assessments that occurred 3 months and 6 months post-enrollment. Results: Assessment completion rates were 71.5% at 3 months, 72.9% at 6 months, and 65.1% for both 3 and 6 months, and did not differ by condition. Using Intent to Treat analyses, the Web + Lozenge condition was associated with a significantly higher 7-day point prevalence tobacco abstinence rate than the Web Only condition at 3 months (43.4% vs. 29.7%, p = .004), at the combined 3 and 6 month assessment of repeated point prevalence (35.6% vs. 23.3%, p = .007), but not at 6 months (44.4% vs. 35.1%, p = .057). Similar results were obtained for smokeless tobacco abstinence. Participants reported being satisfied with their programs and the Web + Lozenge condition participants visited the MyLastDip program more often (p < .001). A composite engagement measure of the number and duration of program visits was positively related to 6-month tobacco abstinence (p = .009). Conclusions: Consistent with previous research, the MyLastDip Web-based tobacco cessation intervention encouraged long-term levels of tobacco and smokeless tobacco abstinence. The addition of nicotine lozenges significantly improved both participant engagement and self-reported 7-day point prevalence tobacco abstinence at 3 months and when considering 3- and 6-month repeated point prevalence tobacco abstinence.http://www.sciencedirect.com/science/article/pii/S2214782914000414Smokeless tobaccoCessationAbstinenceNicotine replacementWebInterneteHealthIntervention |
| spellingShingle | Brian G. Danaher Herbert H. Severson Ryann Crowley Nora van Meter Milagra S. Tyler Chris Widdop Edward Lichtenstein Jon O. Ebbert Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention Internet Interventions Smokeless tobacco Cessation Abstinence Nicotine replacement Web Internet eHealth Intervention |
| title | Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention |
| title_full | Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention |
| title_fullStr | Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention |
| title_full_unstemmed | Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention |
| title_short | Randomized controlled trial examining the adjunctive use of nicotine lozenges with MyLastDip: An eHealth smokeless tobacco cessation intervention |
| title_sort | randomized controlled trial examining the adjunctive use of nicotine lozenges with mylastdip an ehealth smokeless tobacco cessation intervention |
| topic | Smokeless tobacco Cessation Abstinence Nicotine replacement Web Internet eHealth Intervention |
| url | http://www.sciencedirect.com/science/article/pii/S2214782914000414 |
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