Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region
This clinical report describes immediate tooth auto-transplantation with an autograft of partially demineralized dentin/cementum matrix (pDDM), based on an orthodontic treatment plan for a 16-year-old male patient with a congenital missing tooth (#45). First, vital teeth (#14, #24) were extracted, a...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | https://www.mdpi.com/2079-4983/13/2/82 |
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| author | Masaru Murata Yasuhiro Nakanishi Kaoru Kusano Yukito Hirose Junichi Tazaki Toshiyuki Akazawa Itaru Mizoguchi |
| author_facet | Masaru Murata Yasuhiro Nakanishi Kaoru Kusano Yukito Hirose Junichi Tazaki Toshiyuki Akazawa Itaru Mizoguchi |
| author_sort | Masaru Murata |
| collection | DOAJ |
| description | This clinical report describes immediate tooth auto-transplantation with an autograft of partially demineralized dentin/cementum matrix (pDDM), based on an orthodontic treatment plan for a 16-year-old male patient with a congenital missing tooth (#45). First, vital teeth (#14, #24) were extracted, and root canal filling (#14) was immediately performed with the support of a fixation device. Simultaneously, the tooth (#24) was crushed in an electric mill for 1 min, and the crushed granules were partially demineralized in 2% HNO<sub>3</sub> solution for 20 min as the graft material. Next, the donor tooth was transplanted into the created socket (#45), and stabilized using an enamel bonding agent. The wet pDDM was loaded into the location of the congenital missing tooth, and the flap was repositioned. The bonding agent for stabilization was removed at 28 days, and also small contact points between the transplanted tooth and the upper premolar (#14) were added using photopolymerizable composite resin. X-ray photos were taken sequentially, and there were no postoperative complications. The radiographic images showed that the periodontal ligament space and alveolar ridge line could be observed at 18 months. The pDDM was harmonized with the mandible, and the remodeled bone-like shadow was observed in the graft region. We concluded that immediate tooth transplantation with root canal fillings and autogenous pDDM may be a valuable alternative to dental implanting or bridge formation for patients with a congenital missing tooth, followed by orthodontic treatment. |
| first_indexed | 2024-03-09T23:25:22Z |
| format | Article |
| id | doaj.art-64c75b712e034cafb4371f064f591c8f |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-03-09T23:25:22Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-64c75b712e034cafb4371f064f591c8f2023-11-23T17:19:55ZengMDPI AGJournal of Functional Biomaterials2079-49832022-06-011328210.3390/jfb13020082Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth RegionMasaru Murata0Yasuhiro Nakanishi1Kaoru Kusano2Yukito Hirose3Junichi Tazaki4Toshiyuki Akazawa5Itaru Mizoguchi6Division of Regenerative Medicine, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061-0293, JapanDivision of Fixed Prosthodontics and Oral Implantology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061-0293, JapanDepartment of Oral Implantology, Osaka Dental University, Osaka 573-1121, JapanDivision of Fixed Prosthodontics and Oral Implantology, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061-0293, JapanDivision of Regenerative Medicine, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061-0293, JapanIndustrial Technology and Environment Research Development, Hokkaido Research Organization, Hokkaido 060-0819, JapanDivision of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Tohoku University, Sendai 980-8575, JapanThis clinical report describes immediate tooth auto-transplantation with an autograft of partially demineralized dentin/cementum matrix (pDDM), based on an orthodontic treatment plan for a 16-year-old male patient with a congenital missing tooth (#45). First, vital teeth (#14, #24) were extracted, and root canal filling (#14) was immediately performed with the support of a fixation device. Simultaneously, the tooth (#24) was crushed in an electric mill for 1 min, and the crushed granules were partially demineralized in 2% HNO<sub>3</sub> solution for 20 min as the graft material. Next, the donor tooth was transplanted into the created socket (#45), and stabilized using an enamel bonding agent. The wet pDDM was loaded into the location of the congenital missing tooth, and the flap was repositioned. The bonding agent for stabilization was removed at 28 days, and also small contact points between the transplanted tooth and the upper premolar (#14) were added using photopolymerizable composite resin. X-ray photos were taken sequentially, and there were no postoperative complications. The radiographic images showed that the periodontal ligament space and alveolar ridge line could be observed at 18 months. The pDDM was harmonized with the mandible, and the remodeled bone-like shadow was observed in the graft region. We concluded that immediate tooth transplantation with root canal fillings and autogenous pDDM may be a valuable alternative to dental implanting or bridge formation for patients with a congenital missing tooth, followed by orthodontic treatment.https://www.mdpi.com/2079-4983/13/2/82autograftbonedentinDDMhumanimmediate |
| spellingShingle | Masaru Murata Yasuhiro Nakanishi Kaoru Kusano Yukito Hirose Junichi Tazaki Toshiyuki Akazawa Itaru Mizoguchi Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region Journal of Functional Biomaterials autograft bone dentin DDM human immediate |
| title | Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region |
| title_full | Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region |
| title_fullStr | Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region |
| title_full_unstemmed | Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region |
| title_short | Immediate Tooth Autotransplantation with Root Canal Filling and Partially Demineralized Dentin/Cementum Matrix into Congenital Missing Tooth Region |
| title_sort | immediate tooth autotransplantation with root canal filling and partially demineralized dentin cementum matrix into congenital missing tooth region |
| topic | autograft bone dentin DDM human immediate |
| url | https://www.mdpi.com/2079-4983/13/2/82 |
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