Structure‐based identification of functional residues in the nucleoside‐2′‐O‐methylase domain of Bluetongue virus VP4 capping enzyme
Bluetongue virus (BTV) encodes a single capping protein, VP4, which catalyzes all reactions required to generate cap1 structures on nascent viral transcripts. Further, structural analysis by X‐ray crystallography indicated each catalytic reaction is arranged as a discrete domain, including a nucleos...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | FEBS Open Bio |
| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.fob.2015.02.001 |