Berberine Induces p53-Dependent Apoptosis through Inhibition of DNA Methyltransferase3b in Hep3B Cells
The tumor suppressor gene, p53, is inactivated in the human hepatocellular carcinoma cells line, Hep3B. Berberine has been reported to inhibit the proliferation of cancer cells. This study examined whether apoptosis was induced in berberine-treated Hep3B cells and observed the association between ap...
Main Authors: | Dae-Yeon Kim, Seon-Hyoung Kim, Hee-Tae Cheong, Chang-Six Ra, Ki-Jong Rhee, Bae Dong Jung |
---|---|
Format: | Article |
Language: | English |
Published: |
The Korean Society for Clinical Laboratory Science
2020-03-01
|
Series: | Korean Journal of Clinical Laboratory Science |
Subjects: |
Similar Items
-
Tetrahydroisoquinoline N-methyltransferase from <i>Methylotenera</i> Is an Essential Enzyme for the Biodegradation of Berberine in Soil Water
by: Runying He, et al.
Published: (2022-08-01) -
APR-246—The Mutant TP53 Reactivator—Increases the Effectiveness of Berberine and Modified Berberines to Inhibit the Proliferation of Pancreatic Cancer Cells
by: James Andrew McCubrey, et al.
Published: (2022-02-01) -
Comparative Transcriptomics for Genes Related to Berberine and Berbamine Biosynthesis in Berberidaceae
by: Neha Samir Roy, et al.
Published: (2022-10-01) -
Evaluation of prognostic utility of Ki-67, P53, and O-6-methylguanine-DNA methyltransferase expression in pituitary tumors
by: Chhanda Das, et al.
Published: (2019-10-01) -
Extracellular Spermine Activates DNA Methyltransferase 3A and 3B
by: Taro Fukui, et al.
Published: (2019-03-01)